This is a clinical trial of pergolide mesylate in patients with prolactin secreting pituitary tumors who have had a previous trial of bromocriotine that was ineffective in decreasing serum prolactin levels. The trial requires tests before, during and after daily administration of pergolide for one year. These tests are needed to determine any side effects, prolactin levels, and tumor size.

Project Start
Project End
Budget Start
Budget End
Support Year
24
Fiscal Year
1989
Total Cost
Indirect Cost
Name
Upstate Medical University
Department
Type
DUNS #
058889106
City
Syracuse
State
NY
Country
United States
Zip Code
13210
Streeten, D H (1995) Idiopathic edema. Pathogenesis, clinical features, and treatment. Endocrinol Metab Clin North Am 24:531-47
Breslau, N A; Weinstock, R S (1988) Regulation of 1,25 (OH)2D synthesis in hypoparathyroidism and pseudohypoparathyroidism. Am J Physiol 255:E730-6
Haas, D C; Anderson Jr, G H; Streeten, D H (1985) Role of angiotensin in lethal cerebral hypoperfusion during treatment of acute hypertension. Arch Intern Med 145:1922-4