To study protein breakdown and glucose turnover using infusion of 14C-leucine and 3H-glucose. The effect of insulin infusion or glucose metabolism is studied using euglycemic clamp technique and Bergman Minimal Model. Whether supraphysiologic insulin doses can reverse protein breakdown in cancer patients and its explanation in terms of improved glucose metabolism is to be investigated.

Project Start
Project End
Budget Start
Budget End
Support Year
21
Fiscal Year
1989
Total Cost
Indirect Cost
Name
Los Angeles County Harbor-UCLA Medical Center
Department
Type
DUNS #
City
Torrance
State
CA
Country
United States
Zip Code
90509
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