Studies of muscle morphology including determination of muscle fiber types and muscle capillary density in patients with lipodystrophy will be accomplished in order to gain an understanding aspects of insulin resistance in congential lipodystrophy. Muscle volume will be quantified by magnetic resonance imaging of the whole body and the presence of fat in peritoneal and retroperitoneal distribution will be determined. Abnormalities in muscle energy metabolism will be determined by 31P nuclear magnetic spectroscopy.

Project Start
2001-12-01
Project End
2002-11-30
Budget Start
Budget End
Support Year
30
Fiscal Year
2002
Total Cost
$321,374
Indirect Cost
City
Dallas
State
TX
Country
United States
Zip Code
75390
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