This is a phase III trial of Zoledronate, a third generation bisphosphonate which is a more potent inhibitor of osteoclasts than earlier bisphosphonates, in two dose levels verskus pamidronate (Aredia). The latter drug has been shown (in combination with anti-neoplastic agents) to decrease significantly the proportion of patients with skeletal complications due to lytic bone disease associated with multiple myeloma and breast cancer.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
5M01RR001346-20
Application #
6450112
Study Section
National Center for Research Resources Initial Review Group (RIRG)
Project Start
2000-12-01
Project End
2001-11-30
Budget Start
Budget End
Support Year
20
Fiscal Year
2001
Total Cost
Indirect Cost
Name
University of Texas Health Science Center San Antonio
Department
Type
DUNS #
800772162
City
San Antonio
State
TX
Country
United States
Zip Code
78229
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