Abstract

The CRC is designed to serve as a facility for patient-based fundamental and applied research. The following studies are among those presently planned for facility: The Effect of Betaine on Cognitive Function, Behavior, Platelets and Amino Acid Patterns in Homocystinuria. Determination of Renal Iodide Clearance as a Function of Chloride Clearance in the Salt Deplete and the Salt Replete State. Use of the Fractional Excretion of Lithium to Study Basal and Salt-loaded Electrolyte Handling by the Kidneys of Hypertensive and Normotensive Patients. Use of the Biologic Decay of Na22 for Estimation of Human Sodium Intake. Determination of Net Mineralocorticoid Activity in Pregnant Patients by Determining Rectal Potential Differences. Determination of the Effect of Insulin on Sodium Excretion in Obese and Non-obese Individuals. Study of the Mechanism of Edema in Idiopathic Edema, and Determining the Effects of Therapy. Effect of Insulin on Fractional Sodium Excretion in the Insulin-Resistant Obese.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
5M01RR002303-03
Application #
3090318
Study Section
General Clinical Research Centers Committee (CLR)
Project Start
1984-12-01
Project End
1987-11-30
Budget Start
1986-12-01
Budget End
1987-11-30
Support Year
3
Fiscal Year
1987
Total Cost
Indirect Cost

  Institution

Name
University of Mississippi Medical Center
Department
Type
Schools of Medicine
DUNS #
928824473
City
Jackson
State
MS
Country
United States
Zip Code
39216

  Publications

Johnson, W G; Hinkle, L K; Carr, R E et al. (1997) Dietary and exercise interventions for juvenile obesity: long-term effect of behavioral and public health models. Obes Res 5:257-61
Johnson, W G; Carr-Nangle, R E; Bergeron, K C (1995) Macronutrient intake, eating habits, and exercise as moderators of menstrual distress in healthy women. Psychosom Med 57:324-30
Johnson, W G; Corrigan, S A; Lemmon, C R et al. (1994) Energy regulation over the menstrual cycle. Physiol Behav 56:523-7
Beckham, J C; Krug, L M; Penzien, D B et al. (1992) The relationship of ovarian steroids, headache activity and menstrual distress: a pilot study with female migraineurs. Headache 32:292-7
Montani, M; Subramony, S H; Langford, H G et al. (1992) Case report: autonomic postganglionic denervation--sural nerve and saphenous vein biopsy. Am J Med Sci 303:324-8
Langford, H G; Curb, J D; Pressel, S et al. (1991) Effect of thiazide-based therapy on serum alkaline phosphatase. Hypertension Detection and Follow-up Group. J Hum Hypertens 5:333-8
Langford, H G (1991) Sodium-potassium interaction in hypertension and hypertensive cardiovascular disease. Hypertension 17:I155-7
Langford, H G; Cushman, W C; Hsu, H (1991) Chronic effect of KCl on black-white differences in plasma renin activity, aldosterone, and urinary electrolytes. Am J Hypertens 4:399-403
Kang, S S; Wong, P W; Bock, H G et al. (1991) Intermediate hyperhomocysteinemia resulting from compound heterozygosity of methylenetetrahydrofolate reductase mutations. Am J Hum Genet 48:546-51
Langford, H G; Cutter, G; Oberman, A et al. (1990) The effect of thiazide therapy on glucose, insulin and cholesterol metabolism and of glucose on potassium: results of a cross-sectional study in patients from the Hypertension Detection and Follow-up Program. J Hum Hypertens 4:491-500

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