EXCEED THE SPACE PROVIDED. The Clinical Research Center of the Brigham and Women's Hospital (BWH) has as its major goal the application of basic research knowledge to better understand, diagnose, and treat human disease. To achieve this aim, interdisciplinary patient-oriented research is carried out by members of Departments at the BWH (Medicine, Surgery, Women's Health, Neonatology, Obstetrics and Gynecplogy, and Radiology). With the establishment of the Ambulatory GCRC for Cancer Research, the diversity of our GCRC has increased. Users of the GRCR also include scientists at other hospital institutions in the Harvard Medical Area (Harvard School of Public Health, Joslin Diabetes Foundation, and Children's Hospital Medical Center). The presence of the Intensive Physiological Monitoring (IPM) Core provides a powerful resource for BWH and Harvard Medical area researchers to study complex physiology in a variety of disorders. The establishment of an Imaging Core brings to GCRC investigators a powerful new tool to unravel the physiologic and pathophysiologic underpinnings human of health and disease. Finally, a national focus has been on understanding the molecular and genetic basis of human disease so as to provide early diagnosis and to develop novel therapeutic regimens. To this end BWH GCRC investigators have broadened their research efforts to forge collaborative ties with other institutions and their GCRC's as well aswith basic and clinical researchers in both the national and international communities.
| Scheuermaier, Karine; Münch, Mirjam; Ronda, Joseph M et al. (2018) Improved cognitive morning performance in healthy older adults following blue-enriched light exposure on the previous evening. Behav Brain Res 348:267-275 |
| Rachmin, Inbal; O'Meara, Caitlin C; Ricci-Blair, Elisabeth M et al. (2017) Soluble interleukin-13r?1: a circulating regulator of glucose. Am J Physiol Endocrinol Metab 313:E663-E671 |
| Buxton, Orfeu M; Pavlova, Milena K; O'Connor, Shawn P et al. (2017) Lack of change in glucose metabolism in eszopiclone-treated primary insomnia patients. Nat Sci Sleep 9:187-198 |
| Juraschek, Stephen P; Miller 3rd, Edgar R; Weaver, Connie M et al. (2017) Effects of Sodium Reduction and the DASH Diet in Relation to Baseline Blood Pressure. J Am Coll Cardiol 70:2841-2848 |
| Bray, G A; Ryan, D H; Johnson, W et al. (2017) Markers of dietary protein intake are associated with successful weight loss in the POUNDS Lost trial. Clin Obes 7:166-175 |
| Bianchi, Matt T; Phillips, Andrew J K; Wang, Wei et al. (2017) Statistics for Sleep and Biological Rhythms Research. J Biol Rhythms 32:7-17 |
| Swanson, C; Shea, S A; Wolfe, P et al. (2017) 24-hour profile of serum sclerostin and its association with bone biomarkers in men. Osteoporos Int 28:3205-3213 |
| Juraschek, Stephen P; Woodward, Mark; Sacks, Frank M et al. (2017) Time Course of Change in Blood Pressure From Sodium Reduction and the DASH Diet. Hypertension 70:923-929 |
| Hron, Bridget M; Ebbeling, Cara B; Feldman, Henry A et al. (2017) Hepatic, adipocyte, enteric and pancreatic hormones: response to dietary macronutrient composition and relationship with metabolism. Nutr Metab (Lond) 14:44 |
| Rahman, Shadab A; St Hilaire, Melissa A; Chang, Anne-Marie et al. (2017) Circadian phase resetting by a single short-duration light exposure. JCI Insight 2:e89494 |
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