This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This research, with the University of Wisconsin's Pediatric Asthma Clinical Research Program, will test whether and how a Web-based telehealth nursing care support system can increase asthma symptom-free days and adherence to asthma controller medication of children, age 4-12, with moderate persistent or severe persistent asthma. CHESS (Comprehensive Health Enhancement Support System), the proposed intervention, will integrate monthly telephone nurse case management through several healthcare organizations into its existing services. This will allow families to share asthma data with the nurse and the nurse to create educational links within CHESS to help pediatric patients and families gain mastery in asthma self care. Secondary aims include testing whether CHESS (with the case management feature) improves lung function and parent and child quality of life, and reduces unplanned asthma-related healthcare utilization. This study is community-wide and will include (a) Madison's four managed care organizations, Deancare, Physicians Plus, Group Health Cooperative, and Unity, (b) Milwaukee County managed care organization Managed Health Services, and (c) The Wisconsin Department of Health and Family Services Medicaid division. Four-hundred (400) children with asthma and primary parent will be recruited; one-third of the sample will be ethnic minorities. Subjects will be randomized to receive Standard Care or CHESS (with case management). Data Collection includes: (1) Claims data for pharmacy refills, (2) spirometry readings, (3) 5 survey questionnaires, (4) 5 two-week symptom diaries, (5) 2 interviews (one at intake and one at exit), and (6) CHESS usage data. Diary and survey data will be collected at 0, 3, 6, 9 and 12 months. Nursing case management and CHESS have both been shown to have positive outcomes in chronic disease management, however this is the first opportunity to study them in combination.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
5M01RR003186-21
Application #
7375513
Study Section
National Center for Research Resources Initial Review Group (RIRG)
Project Start
2005-12-01
Project End
2006-11-30
Budget Start
2005-12-01
Budget End
2006-11-30
Support Year
21
Fiscal Year
2006
Total Cost
$25,444
Indirect Cost
Name
University of Wisconsin Madison
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
161202122
City
Madison
State
WI
Country
United States
Zip Code
53715
Burgess-Hull, Albert J; Roberts, Linda J; Piper, Megan E et al. (2018) The social networks of smokers attempting to quit: An empirically derived and validated classification. Psychol Addict Behav 32:64-75
Kelly, Elizabeth A; Esnault, Stephane; Liu, Lin Ying et al. (2017) Mepolizumab Attenuates Airway Eosinophil Numbers, but Not Their Functional Phenotype, in Asthma. Am J Respir Crit Care Med 196:1385-1395
Shen, Zhong-Jian; Hu, Jie; Kashi, Venkatesh P et al. (2017) Epstein-Barr Virus-induced Gene 2 Mediates Allergen-induced Leukocyte Migration into Airways. Am J Respir Crit Care Med 195:1576-1585
Anderson, Halie M; Lemanske Jr, Robert F; Evans, Michael D et al. (2017) Assessment of wheezing frequency and viral etiology on childhood and adolescent asthma risk. J Allergy Clin Immunol 139:692-694
Gomez, Jose L; Yan, Xiting; Holm, Carole T et al. (2017) Characterisation of asthma subgroups associated with circulating YKL-40 levels. Eur Respir J 50:
Kelly, Elizabeth A; Esnault, Stephane; Johnson, Sean H et al. (2016) Human eosinophil activin A synthesis and mRNA stabilization are induced by the combination of IL-3 plus TNF. Immunol Cell Biol 94:701-8
Bray, Bethany C; Smith, Rachel A; Piper, Megan E et al. (2016) Transitions in Smokers' Social Networks After Quit Attempts: A Latent Transition Analysis. Nicotine Tob Res 18:2243-2251
Dougherty, Ryan J; Ellingson, Laura D; Schultz, Stephanie A et al. (2016) Meeting physical activity recommendations may be protective against temporal lobe atrophy in older adults at risk for Alzheimer's disease. Alzheimers Dement (Amst) 4:14-7
Johansson, Mats W; Evans, Michael D; Crisafi, Gina M et al. (2016) Serum periostin is associated with type 2 immunity in severe asthma. J Allergy Clin Immunol 137:1904-1907.e2
Lee, Yong Gyu; Jeong, Jong Jin; Nyenhuis, Sharmilee et al. (2015) Recruited alveolar macrophages, in response to airway epithelial-derived monocyte chemoattractant protein 1/CCl2, regulate airway inflammation and remodeling in allergic asthma. Am J Respir Cell Mol Biol 52:772-84

Showing the most recent 10 out of 459 publications