This subproject is one of many research subprojects utilizing theresources provided by a Center grant funded by NIH/NCRR. The subproject andinvestigator (PI) may have received primary funding from another NIH source,and thus could be represented in other CRISP entries. The institution listed isfor the Center, which is not necessarily the institution for the investigator.The main goal of the present study is to determine tolerability and safety of lovastatin used in two different doses, administered on a chronic oral schedule in children with neurofibromatosis type I and learning disabilities including deficits in attention; working memory; learning acquisition; memory storage; and retrieval/access of learned material.
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