Abstract

The goal of this resource contract is to facilitate the further development of schistosomiasis research. Besides providing research materials to investigators who could not reasonably work on this parasitic infection otherwise, it serves as a backup facility for investigators who have had problems with their own established parasite colonies. In addition to supplying schistosome materials, the contract will provide training and technical assistance to other laboratories on snail cultivation, parasite collection and host infection.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research and Development Contracts (N01)
Project #
N01AI055270-000
Application #
2296471
Study Section
Project Start
1995-08-01
Project End
2002-07-31
Budget Start
1995-08-01
Budget End
1996-07-31
Support Year
Fiscal Year
1995
Total Cost
Indirect Cost

  Institution

Name
Biomedical Research Institute
Department
Type
DUNS #
City
Rockville
State
MD
Country
United States
Zip Code
20852

  Publications

Vasta, James D; Lesage, Karen E; Fried, Bernard (2011) A simple method for culturing neonatal Biomphalaria glabrata snails. J Parasitol 97:746-7
Ray, Debalina; Williams, David L (2011) Characterization of the phytochelatin synthase of Schistosoma mansoni. PLoS Negl Trop Dis 5:e1168
Cogswell, Alexis A; Collins 3rd, James J; Newmark, Phillip A et al. (2011) Whole mount in situ hybridization methodology for Schistosoma mansoni. Mol Biochem Parasitol 178:46-50
Rinaldi, Gabriel; Suttiprapa, Sutas; Brindley, Paul J (2011) Quantitative retrotransposon anchored PCR confirms transduction efficiency of transgenes in adult Schistosoma mansoni. Mol Biochem Parasitol 177:70-6
Oke, Tolulope T; Moskovitz, Jackob; Williams, David L (2009) Characterization of the methionine sulfoxide reductases of Schistosoma mansoni. J Parasitol 95:1421-8
Bazzone, Lindsey E; Smith, Patrick M; Rutitzky, Laura I et al. (2008) Coinfection with the intestinal nematode Heligmosomoides polygyrus markedly reduces hepatic egg-induced immunopathology and proinflammatory cytokines in mouse models of severe schistosomiasis. Infect Immun 76:5164-72
Shainheit, Mara G; Saraceno, Rosita; Bazzone, Lindsey E et al. (2007) Disruption of interleukin-27 signaling results in impaired gamma interferon production but does not significantly affect immunopathology in murine schistosome infection. Infect Immun 75:3169-77
Harvie, Marina; Jordan, Thomas William; La Flamme, Anne Camille (2007) Differential liver protein expression during schistosomiasis. Infect Immun 75:736-44
Cass, Cynthia L; Johnson, Jeffrey R; Califf, Lindsay L et al. (2007) Proteomic analysis of Schistosoma mansoni egg secretions. Mol Biochem Parasitol 155:84-93
Massa, Daniel R; Chejlava, Michael J; Fried, Bernard et al. (2007) High performance column liquid chromatographic analysis of selected carboxylic acids in Biomphalaria glabrata patently infected with Schistosoma mansoni. Parasitol Res 101:925-8

Showing the most recent 10 out of 78 publications