Project Start
1985-12-02
Project End
1990-12-01
Budget Start
1990-08-14
Budget End
1990-12-01
Support Year
Fiscal Year
1990
Total Cost
Indirect Cost
Name
Baylor College of Medicine
Department
Type
Schools of Medicine
DUNS #
074615394
City
Houston
State
TX
Country
United States
Zip Code
77030
Gilbert, B E; Wyde, P R; Wilson, S Z et al. (1993) SP-303 small-particle aerosol treatment of influenza A virus infection in mice and respiratory syncytial virus infection in cotton rats. Antiviral Res 21:37-45
Gilbert, B E; Wyde, P R; Ambrose, M W et al. (1992) Further studies with short duration ribavirin aerosol for the treatment of influenza virus infection in mice and respiratory syncytial virus infection in cotton rats. Antiviral Res 17:33-42
Gilbert, B E; Wyde, P R; Wilson, S Z et al. (1991) Aerosol and intraperitoneal administration of ribavirin and ribavirin triacetate: pharmacokinetics and protection of mice against intracerebral infection with influenza A/WSN virus. Antimicrob Agents Chemother 35:1448-53
Ambrose, M W; Wyde, P R; Ewasyshyn, M et al. (1991) Evaluation of the immunogenicity and protective efficacy of a candidate parainfluenza virus type 3 subunit vaccine in cotton rats. Vaccine 9:505-11
Wyde, P R; Ambrose, M W; Meyer, H L et al. (1990) Evaluation of the toxicity and antiviral activity of carbocyclic 3-deazaadenosine against respiratory syncytial and parainfluenza type 3 viruses in tissue culture and in cotton rats. Antiviral Res 14:215-25
Wyde, P R; Ambrose, M W; Meyer, H L et al. (1990) Toxicity and antiviral activity of LY253963 against respiratory syncytial and parainfluenza type 3 viruses in tissue culture and in cotton rats. Antiviral Res 14:237-47
Wyde, P R; Gilbert, B E; Ambrose, M W (1989) Comparison of the anti-respiratory syncytial virus activity and toxicity of papaverine hydrochloride and pyrazofurin in vitro and in vivo. Antiviral Res 11:15-26
Gilbert, B E; Wyde, P R (1988) Pharmacokinetics of ribavirin aerosol in mice. Antimicrob Agents Chemother 32:117-21
Gruber, W C; Wilson, S Z; Throop, B J et al. (1987) Immunoglobulin administration and ribavirin therapy: efficacy in respiratory syncytial virus infection of the cotton rat. Pediatr Res 21:270-4
Wyde, P R; Wilson, S Z; Petrella, R et al. (1987) Efficacy of high dose-short duration ribavirin aerosol in the treatment of respiratory syncytial virus infected cotton rats and influenza B virus infected mice. Antiviral Res 7:211-20

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