Project Start
1987-08-01
Project End
1992-07-31
Budget Start
1988-03-21
Budget End
1988-07-31
Support Year
Fiscal Year
1988
Total Cost
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Type
Schools of Dentistry/Oral Hygn
DUNS #
791277940
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Zou, R; Kawashima, E; Freeman, G A et al. (2000) Design, synthesis, and antiviral evaluation of 2-deoxy-D-ribosides of substituted benzimidazoles as potential agents for human cytomegalovirus infections. Nucleosides Nucleotides Nucleic Acids 19:125-53
Jacobson, J G; Renau, T E; Nassiri, M R et al. (1999) Nonnucleoside pyrrolopyrimidines with a unique mechanism of action against human cytomegalovirus. Antimicrob Agents Chemother 43:1888-94
Swayze, E E; Drach, J C; Wotring, L L et al. (1997) Synthesis, antiproliferative and antiviral activity of imidazo[4,5-d]isothiazole nucleosides as 5:5 fused analogs of nebularine and 6-methylpurine ribonucleoside. J Med Chem 40:771-84
Zou, R; Drach, J C; Townsend, L B (1997) Design, synthesis, and antiviral evaluation of 2-substituted 4,5-dichloro- and 4,6-dichloro-1-beta-D-ribofuranosylbenzimidazoles as potential agents for human cytomegalovirus infections. J Med Chem 40:802-10
Meade, E A; Wotring, L L; Drach, J C et al. (1997) Synthesis and antiproliferative and antiviral activity of carbohydrate-modified pyrrolo[2,3-d]pyridazin-7-one nucleosides. J Med Chem 40:794-801
Renau, T E; Kennedy, C; Ptak, R G et al. (1996) Synthesis of non-nucleoside analogs of toyocamycin, sangivamycin, and thiosangivamycin: the effect of certain 4- and 4,6-substituents on the antiviral activity of pyrrolo[2,3-d]pyrimidines. J Med Chem 39:3470-6
Zou, R; Ayres, K R; Drach, J C et al. (1996) Synthesis and antiviral evaluation of certain disubstituted benzimidazole ribonucleosides. J Med Chem 39:3477-82
Krawczyk, S H; Renau, T E; Nassiri, M R et al. (1995) Synthesis and evaluation of certain thiosangivamycin analogs as potential inhibitors of cell proliferation and human cytomegalovirus. J Med Chem 38:4115-9
Townsend, L B; Devivar, R V; Turk, S R et al. (1995) Design, synthesis, and antiviral activity of certain 2,5,6-trihalo-1-(beta-D-ribofuranosyl)benzimidazoles. J Med Chem 38:4098-105
Devivar, R V; Kawashima, E; Revankar, G R et al. (1994) Benzimidazole ribonucleosides: design, synthesis, and antiviral activity of certain 2-(alkylthio)- and 2-(benzylthio)-5,6-dichloro-1-(beta-D-ribofuranosyl)benzimidazoles. J Med Chem 37:2942-9

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