This contract is for the continued support of a clinical trial to investigate the efficacy of monoclonal antibodies in preventing kidney graft rejection. The contractor will enroll at least fifty patients into a randomized trial in which, upon transplant, the patient will receive either conventional immunosuppression or a combination of conventional therapy plus monoclonal antibody. The patients will be followed and data collected on various parameters which would show differences in the effectiveness of the two treatment protocols in preventing rejection.

Project Start
1988-07-01
Project End
1992-06-30
Budget Start
1991-05-10
Budget End
1992-06-30
Support Year
Fiscal Year
1991
Total Cost
Indirect Cost
Name
University of Kentucky
Department
Type
Schools of Medicine
DUNS #
832127323
City
Lexington
State
KY
Country
United States
Zip Code
40506
Waid, T H; Lucas, B A; Thompson, J S et al. (1997) Treatment of renal allograft rejection with T10B9.1A31 or OKT3: final analysis of a phase II clinical trial. Transplantation 64:274-81