This contract is for a Registry and Repository for Antiphospholipid Syndrome (APS) that will enable investigators to identify basic immunological and genetic abnormalities, pathophysiological mechanisms contributing to thrombosis, fetal loss, and other clinical manifestations of APS. In addition, the Registry will be a key resource for projects aimed at improving methods of diagnosis and evaluating more effective and safer methods of treatment and prophylaxis. The registry will collect and update clinical, demographic, and laboratory data on patients with APS, asymptomatic patients with antiphospholipid antibodies, and certain individuals with serological and/or clinical features that fall within an expanded concept of APS. The availability of new classification criteria will allow resolution of the problems associated with disease heterogeneity and better comparisons among clinical research projects. The registry is a multi-center, multi-speciality, collaborative project involving a group of leading APS investigators (rheumatologists, hematologists, neurologists and obstetricians) at 8 academic medical centers.

Project Start
2000-09-28
Project End
2005-09-29
Budget Start
2000-09-28
Budget End
2001-09-29
Support Year
Fiscal Year
2000
Total Cost
$486,503
Indirect Cost
Name
University of North Carolina Chapel Hill
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
078861598
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599