Agency
National Institute of Health (NIH)
Institute
Division of Cancer Treatment (NCI)
Type
Research and Development Contracts (N01)
Project #
N01CM007306-005
Application #
2299686
Study Section
Project Start
1990-05-01
Project End
1995-05-31
Budget Start
1992-06-30
Budget End
1992-11-30
Support Year
Fiscal Year
1992
Total Cost
Indirect Cost
Name
University of Wisconsin Madison
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
161202122
City
Madison
State
WI
Country
United States
Zip Code
53715
Hutson, P R; Tutsch, K D; Rago, R et al. (1998) Renal clearance, tissue distribution, and CA-125 responses in a phase I trial of suramin. Clin Cancer Res 4:1429-36
Berlin, J; Stewart, J A; Storer, B et al. (1998) Phase I clinical and pharmacokinetic trial of penclomedine using a novel, two-stage trial design for patients with advanced malignancy. J Clin Oncol 16:1142-9
Berlin, J; Tutsch, K D; Hutson, P et al. (1997) Phase I clinical and pharmacokinetic study of oral carboxyamidotriazole, a signal transduction inhibitor. J Clin Oncol 15:781-9
McGinn, C J; Kunugi, K A; Tutsch, K D et al. (1996) Leucovorin modulation of 5-iododeoxyuridine radiosensitization: a phase I study. Clin Cancer Res 2:1299-305
Schiller, J H; Storer, B; Tutsch, K et al. (1994) Phase I trial of 3-hour infusion of paclitaxel with or without granulocyte colony-stimulating factor in patients with advanced cancer. J Clin Oncol 12:241-8
Bailey, H H; Mulcahy, R T; Tutsch, K D et al. (1994) Phase I clinical trial of intravenous L-buthionine sulfoximine and melphalan: an attempt at modulation of glutathione. J Clin Oncol 12:194-205
Hutson, P R; Tutsch, K; Spriggs, D et al. (1993) Evidence of an absorption phase after short intravenous suramin infusions. Cancer Chemother Pharmacol 31:495-9
Schiller, J H; Storer, B; Arzoomanian, R et al. (1993) Phase I trial of mitoxantrone and granulocyte-macrophage colony-stimulating factor (GM-CSF) in patients with advanced solid malignancies. Invest New Drugs 11:291-300
Schiller, J H; Witt, P L; Storer, B et al. (1992) Clinical and biologic effects of combination therapy with gamma-interferon and tumor necrosis factor. Cancer 69:562-71
Bailey, H; Wilding, G; Tutsch, K D et al. (1992) A phase I trial of 5-fluorouracil, leucovorin, and dipyridamole given by concurrent 120-h continuous infusions. Cancer Chemother Pharmacol 30:297-302