Preclinical Assessment of Monoclonal Antibodies

Schroff, Robert W.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: Division of Cancer Treatment (NCI)
• Type: Research and Development Contracts (N01)
• Project #: N01CM067719-005
• Application #: 3614178
• Project Start: 1986-02-01
• Project End: 1989-01-31
• Budget Start: 1987-07-30
• Budget End: 1988-01-31
• Fiscal Year: 1987

Institution

• Name: Neorx Corporation
• City: Seattle
• State: WA
• Country: United States
• Zip Code: 98119

Publications

Morgan Jr, A C; Sullivan, W; Graves, S et al. (1989) Murine monoclonal IgG3 to human colorectal tumor-associated antigens: enhancement of antibody-dependent cell-mediated cytotoxicity by interleukin 2. Cancer Res 49:2773-6

Woodhouse, C S; Morgan Jr, A C (1989) Murine monoclonal IgG3 antibodies to human colorectal tumor-associated antigens: production and characterization of antibodies active in both antibody-dependent cellular cytotoxicity and complement-mediated cytolysis. Cancer Res 49:2766-72

Fritzberg, A R; Abrams, P G; Beaumier, P L et al. (1988) Specific and stable labeling of antibodies with technetium-99m with a diamide dithiolate chelating agent. Proc Natl Acad Sci U S A 85:4025-9