The contractor shall analyze bulk pharmaceutical substances and formulated drug products for new anti-AIDS agents. Reports of the analyses will be used as a basis for assessing the suitability of these materials for use for screening, pharmacological studies, toxicological studies, formulation studies or for clinical trials. Data provided in these analytical reports will be supplied to the Food and Drug Administration as part of the new IND filings for new anti-AIDS agents. Historical summaries of the data are used in preparing specifications for the various bulk pharmaceutical substances. These specifications are used in procurement actions as well as for the routine quality control of these materials.

Agency
National Institute of Health (NIH)
Institute
Division of Cancer Treatment (NCI)
Type
Research and Development Contracts (N01)
Project #
N01CM067864-003
Application #
3614271
Study Section
Project Start
1986-09-30
Project End
1991-09-29
Budget Start
1988-06-11
Budget End
1989-09-29
Support Year
Fiscal Year
1988
Total Cost
Indirect Cost
Name
Sri International
Department
Type
DUNS #
City
Menlo Park
State
CA
Country
United States
Zip Code
94025
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Hettiarachchi, K; Cheung, A P (1991) Capillary electrophoresis analysis of concanavalin A and its succinyl derivative. J Pharm Biomed Anal 9:835-41
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Olson, L L; Cheung, A P (1990) 31P-NMR assay of phosphatidylcholine and phosphatidylethanolamine in AL721. J Pharm Biomed Anal 8:725-8
Cheung, A P; Olson, L L (1990) 1H-NMR assay of phosphatidylcholine and phosphatidylethanolamine in AL721. J Pharm Biomed Anal 8:729-34