Agency
National Institute of Health (NIH)
Institute
Division of Cancer Treatment (NCI)
Type
Research and Development Contracts (N01)
Project #
N01CM067912-004
Application #
3614447
Study Section
Project Start
1986-06-30
Project End
1989-06-29
Budget Start
1988-07-01
Budget End
1989-06-29
Support Year
Fiscal Year
1988
Total Cost
Indirect Cost
Name
University of Kansas Lawrence
Department
Type
Schools of Pharmacy
DUNS #
072933393
City
Lawrence
State
KS
Country
United States
Zip Code
66045
Rajewski, R A; Traiger, G; Bresnahan, J et al. (1995) Preliminary safety evaluation of parenterally administered sulfoalkyl ether beta-cyclodextrin derivatives. J Pharm Sci 84:927-32
Sisco, J M; Stella, V J (1992) An unexpected hydrolysis pH-rate profile, at pH values less than 7, of the labile imide, ICRF-187: (+)-1,2-bis-(3,5-dioxopiperazin-1-yl)propane. Pharm Res 9:1209-14
Sisco, J M; Stella, V J (1992) Is ICRF-187 [(+)-1,2-bis(3,5-dioxopiperazinyl-1-yl)propane] unusually reactive for an imide? Pharm Res 9:1076-82
Mathew, A E; Mejillano, M R; Nath, J P et al. (1992) Synthesis and evaluation of some water-soluble prodrugs and derivatives of taxol with antitumor activity. J Med Chem 35:145-51
Waugh, W N; Trissel, L A; Stella, V J (1991) Stability, compatibility, and plasticizer extraction of taxol (NSC-125973) injection diluted in infusion solutions and stored in various containers. Am J Hosp Pharm 48:1520-4
Prankerd, R J; Stella, V J (1990) The use of oil-in-water emulsions as a vehicle for parenteral drug administration. J Parenter Sci Technol 44:139-49
al-Razzak, L A; Benedetti, A E; Waugh, W N et al. (1990) Chemical stability of pentostatin (NSC-218321), a cytotoxic and immunosuppressant agent. Pharm Res 7:452-60
Prankerd, R J; Frank, S G; Stella, V J (1988) Preliminary development and evaluation of a parenteral emulsion formulation of penclomedine (NSC-338720;3,5-dichloro-2,4-dimethoxy-6-trichloromethylpyridine): a novel, practically water insoluble cytotoxic agent. J Parenter Sci Technol 42:76-81
Paborji, M; Waugh, W N; Stella, V J (1987) Mechanistic investigation of the degradation of sulfamic acid 1,7-heptanediyl ester, an experimental cytotoxic agent, in water and 18oxygen-enriched water. J Pharm Sci 76:161-5