Conduct studies to monitor the integrity and reliability of in vivo tumor systems and rodents used in the cancer drug development program of the development Therapeutics Program (DTP). To be accomplished through collection of kinetic data and evaluation of drug testing using standard and experimental agents. Develop in vivo protocols for candidate tumor models from the human tumor cell line diseaseoriented screen so as to provide the necessary tools for the followup of active materials identified as having potential for development for possible clinical trial. This protocol development will include the testing of standard and experimental drugs to evaluate their effectiveness against new in vivo models. In addition, host animals for these tumor systems must be monitored and subjected to vigorous quality control.

Agency
National Institute of Health (NIH)
Institute
Division of Cancer Treatment (NCI)
Type
Research and Development Contracts (N01)
Project #
N01CM097553-000
Application #
3616588
Study Section
Project Start
1989-03-25
Project End
1994-02-09
Budget Start
1989-03-25
Budget End
1990-02-09
Support Year
Fiscal Year
1989
Total Cost
Indirect Cost
Name
Southern Research Institute
Department
Type
DUNS #
006900526
City
Birmingham
State
AL
Country
United States
Zip Code
35205