Abstract

This project is a collaborative effort that seeks the development of new computer-based support systems that provide the radiotherapist and medical physicist in the field of radiation therapy treatment planning with new tools that will help to make three dimensional treatment planning a routine activity. The contractor will participate as a member of Collaborative Working Group and will participate in the design development and evaluation of computer based tools that accomplish the specific tasks: (a1) Automatically and rapidly extract anatomical features from multiple CT images to construct three dimensional volumes that are needed for the definition of critical structures in the treatment planning process. (a2) Assist physicians in the tumor localization process on the CT scans for treatment planning purposes. (a3) Assist the physician in the generation of treatment volume contours given the tumor volume localization information. (a4) Make """"""""first-guess"""""""" choices for an optimal treatment plan. (a5) Present alternative """"""""optimal"""""""" plans for the radiotherapist using the full capabilities of a three dimensional treatment planning system. (a6) Provide means for rapidly and interactively comparing digitally produced portal images with CT reconstructions that represent the patient's anatomical configuration in the treatment position.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
Division of Cancer Treatment (NCI)
Type
Research and Development Contracts (N01)
Project #
N01CM097564-009
Application #
3616621
Study Section
Project Start
1989-03-01
Project End
1994-02-28
Budget Start
1994-01-12
Budget End
1994-02-28
Support Year
Fiscal Year
1994
Total Cost
Indirect Cost

  Institution

Name
Washington University
Department
Type
Schools of Medicine
DUNS #
062761671
City
Saint Louis
State
MO
Country
United States
Zip Code
63130

  Publications

Michalski, J M; Graham, M V; Bosch, W R et al. (1996) Prospective clinical evaluation of an electronic portal imaging device. Int J Radiat Oncol Biol Phys 34:943-51
Tinger, A; Michalski, J M; Bosch, W R et al. (1996) An analysis of intratreatment and intertreatment displacements in pelvic radiotherapy using electronic portal imaging. Int J Radiat Oncol Biol Phys 34:683-90
Graham, M V; Jain, N L; Kahn, M G et al. (1996) Evaluation of an objective plan-evaluation model in the three dimensional treatment of nonsmall cell lung cancer. Int J Radiat Oncol Biol Phys 34:469-74
Bosch, W R; Low, D A; Gerber, R L et al. (1995) The Electronic View Box: a software tool for radiation therapy treatment verification. Int J Radiat Oncol Biol Phys 31:135-42
Wong, J; Yan, D; Michalski, J et al. (1995) The cumulative verification image analysis tool for offline evaluation of portal images. Int J Radiat Oncol Biol Phys 33:1301-10
Graham, M V; Matthews, J W; Harms Sr, W B et al. (1994) Three-dimensional radiation treatment planning study for patients with carcinoma of the lung. Int J Radiat Oncol Biol Phys 29:1105-17
Valicenti, R K; Michalski, J M; Bosch, W R et al. (1994) Is weekly port filming adequate for verifying patient position in modern radiation therapy? Int J Radiat Oncol Biol Phys 30:431-8
Drzymala, R E; Holman, M D; Yan, D et al. (1994) Integrated software tools for the evaluation of radiotherapy treatment plans. Int J Radiat Oncol Biol Phys 30:909-19
Kahn, M G (1994) Clinical databases and critical care research. Crit Care Clin 10:37-51
Michalski, J M; Wong, J W; Bosch, W R et al. (1993) An evaluation of two methods of anatomical alignment of radiotherapy portal images. Int J Radiat Oncol Biol Phys 27:1199-206

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