Agency
National Institute of Health (NIH)
Institute
Division of Cancer Prevention And Control (NCI)
Type
Research and Development Contracts (N01)
Project #
N01CN025025-001
Application #
6994818
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
2004
Total Cost
Indirect Cost
Name
University of Michigan /Inc/
Department
Type
DUNS #
City
State
Country
Zip Code
Andreadi, Catherine; Britton, Robert G; Patel, Ketan R et al. (2014) Resveratrol-sulfates provide an intracellular reservoir for generation of parent resveratrol, which induces autophagy in cancer cells. Autophagy 10:524-5
Patel, Ketan R; Andreadi, Catherine; Britton, Robert G et al. (2013) Sulfate metabolites provide an intracellular pool for resveratrol generation and induce autophagy with senescence. Sci Transl Med 5:205ra133
Brown, Victoria A; Patel, Ketan R; Viskaduraki, Maria et al. (2010) Repeat dose study of the cancer chemopreventive agent resveratrol in healthy volunteers: safety, pharmacokinetics, and effect on the insulin-like growth factor axis. Cancer Res 70:9003-11
Patel, Ketan R; Brown, Victoria A; Jones, Donald J L et al. (2010) Clinical pharmacology of resveratrol and its metabolites in colorectal cancer patients. Cancer Res 70:7392-9
Boocock, David J; Faust, Guy E S; Patel, Ketan R et al. (2007) Phase I dose escalation pharmacokinetic study in healthy volunteers of resveratrol, a potential cancer chemopreventive agent. Cancer Epidemiol Biomarkers Prev 16:1246-52
Boocock, David J; Patel, Ketan R; Faust, Guy E S et al. (2007) Quantitation of trans-resveratrol and detection of its metabolites in human plasma and urine by high performance liquid chromatography. J Chromatogr B Analyt Technol Biomed Life Sci 848:182-7