Funding Agency

Agency
National Institute of Health (NIH)
Institute
Division of Cancer Prevention And Control (NCI)
Type
Research and Development Contracts (N01)
Project #
N01CN065031-007
Application #
3621289
Study Section
Project Start
1986-09-30
Project End
Budget Start
1988-04-21
Budget End
1988-06-30
Support Year
Fiscal Year
1988
Total Cost
Indirect Cost

  Institution

Name
University of Kentucky
Department
Type
Schools of Medicine
DUNS #
832127323
City
Lexington
State
KY
Country
United States
Zip Code
40506

  Publications

Kuraguchi, M; Yang, K; Wong, E et al. (2001) The distinct spectra of tumor-associated Apc mutations in mismatch repair-deficient Apc1638N mice define the roles of MSH3 and MSH6 in DNA repair and intestinal tumorigenesis. Cancer Res 61:7934-42
Kuraguchi, M; Edelmann, W; Yang, K et al. (2000) Tumor-associated Apc mutations in Mlh1-/- Apc1638N mice reveal a mutational signature of Mlh1 deficiency. Oncogene 19:5755-63
Shilkaitis, A; Green, A; Steele, V et al. (2000) Neoplastic transformation of mammary epithelial cells in rats is associated with decreased apoptotic cell death. Carcinogenesis 21:227-33
Edelmann, W; Yang, K; Kuraguchi, M et al. (1999) Tumorigenesis in Mlh1 and Mlh1/Apc1638N mutant mice. Cancer Res 59:1301-7
Edelmann, W; Cohen, P E; Kneitz, B et al. (1999) Mammalian MutS homologue 5 is required for chromosome pairing in meiosis. Nat Genet 21:123-7