Abstract

The overall objective of this contract is to identify and clone tumor suppressor genes in B6C3F1 mice. This includes the identification of polymorphic probes in the B6C3F1 mouse using probes that have been mapped to chromosomes in the mouse or other species; identify mouse chromosomes that show a loss of heterozygosity in specific tumor tissue DNAs using RFLP probes; reprobe membranes with selected oncogene probes to determine if certain oncogenes are amplified in tumors studied.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Research and Development Contracts (N01)
Project #
N01ES005305-000
Application #
2308025
Study Section
Project Start
1990-09-30
Project End
1995-09-29
Budget Start
1990-09-30
Budget End
1991-09-29
Support Year
Fiscal Year
1990
Total Cost
Indirect Cost

  Institution

Name
Applied Genetics Laboratories, Inc.
Department
Type
DUNS #
City
Melbourne
State
FL
Country
United States
Zip Code
32904