Abstract

9-Aminoacridine is being tested in Fischer 344/N rats and B6C3F1 mice to determine subchronic toxicity and potential organ toxicity. 9-Aminoacridine is used in vaginal creams to combat vaginitis and cervicitis. Comparison of the dermal and dose-feed routes of exposure indicates that systemic toxicity is best demonstrated using the dose-feed route. A subchronic dose-feed study is underway.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Research and Development Contracts (N01)
Project #
N01ES028004-003016
Application #
3639508
Study Section
Project Start
1983-08-30
Project End
Budget Start
1986-02-03
Budget End
1986-02-18
Support Year
Fiscal Year
1986
Total Cost
Indirect Cost

  Institution

Name
American Biogenics Corporation
Department
Type
DUNS #
City
Woburn
State
MA
Country
United States
Zip Code
01801