Agency
National Institute of Health (NIH)
Institute
Division of Blood Diseases And Resources (NHLBI)
Type
Research and Development Contracts (N01)
Project #
N01HB027091-008
Application #
2661615
Study Section
Project Start
1992-06-18
Project End
2002-06-17
Budget Start
1997-09-26
Budget End
2000-11-10
Support Year
Fiscal Year
1997
Total Cost
Indirect Cost
Name
Southwest Foundation for Biomedical Research
Department
Type
DUNS #
City
San Antonio
State
TX
Country
United States
Zip Code
78245
Rodriguez, Annette R; Hodara, Vida; Murthy, Kruthi et al. (2014) T cell interleukin-15 surface expression in chimpanzees infected with human immunodeficiency virus. Cell Immunol 288:24-30
Huang, Ying; Feld, Jordan J; Sapp, Ronda K et al. (2007) Defective hepatic response to interferon and activation of suppressor of cytokine signaling 3 in chronic hepatitis C. Gastroenterology 132:733-44
Elmowalid, Gamal A; Qiao, Ming; Jeong, Sook-Hyang et al. (2007) Immunization with hepatitis C virus-like particles results in control of hepatitis C virus infection in chimpanzees. Proc Natl Acad Sci U S A 104:8427-32
Rodriguez, Annette R; Arulanandam, Bernard P; Hodara, Vida L et al. (2007) Influence of interleukin-15 on CD8+ natural killer cells in human immunodeficiency virus type 1-infected chimpanzees. J Gen Virol 88:641-51
Wakita, Takaji; Pietschmann, Thomas; Kato, Takanobu et al. (2005) Production of infectious hepatitis C virus in tissue culture from a cloned viral genome. Nat Med 11:791-6
Woollard, David J; Grakoui, Arash; Shoukry, Naglaa H et al. (2003) Characterization of HCV-specific Patr class II restricted CD4+ T cell responses in an acutely infected chimpanzee. Hepatology 38:1297-306
Thomson, Michael; Nascimbeni, Michelina; Havert, Michael B et al. (2003) The clearance of hepatitis C virus infection in chimpanzees may not necessarily correlate with the appearance of acquired immunity. J Virol 77:862-70
Grakoui, Arash; Shoukry, Naglaa H; Woollard, David J et al. (2003) HCV persistence and immune evasion in the absence of memory T cell help. Science 302:659-62
Thomson, M; Nascimbeni, M; Gonzales, S et al. (2001) Emergence of a distinct pattern of viral mutations in chimpanzees infected with a homogeneous inoculum of hepatitis C virus. Gastroenterology 121:1226-33
Dash, S; Kalkeri, G; McClure, H M et al. (2001) Transmission of HCV to a chimpanzee using virus particles produced in an RNA-transfected HepG2 cell culture. J Med Virol 65:276-81

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