Establish a serum repository which will be used under another contract for testing of antibodies to HTLV-III virus, identification of of seropositive donors and the recipients of blood products from these donors, follow-up of recipients, and data analysis.

Agency
National Institute of Health (NIH)
Institute
Division of Blood Diseases And Resources (NHLBI)
Type
Research and Development Contracts (N01)
Project #
N01HB047002-005
Application #
3645353
Study Section
Project Start
1984-05-25
Project End
1985-05-24
Budget Start
1985-09-24
Budget End
1985-05-24
Support Year
Fiscal Year
1985
Total Cost
Indirect Cost
Name
University of Southern California
Department
Type
Schools of Medicine
DUNS #
041544081
City
Los Angeles
State
CA
Country
United States
Zip Code
90033
Operskalski, E A; Stram, D O; Busch, M P et al. (1997) Role of viral load in heterosexual transmission of human immunodeficiency virus type 1 by blood transfusion recipients. Transfusion Safety Study Group. Am J Epidemiol 146:655-61
Operskalski, E A; Busch, M P; Mosley, J W et al. (1997) Comparative rates of disease progression among persons infected with the same or different HIV-1 strains. The Transfusion Safety Study Group. J Acquir Immune Defic Syndr Hum Retrovirol 15:145-50
Zhang, L; Diaz, R S; Ho, D D et al. (1997) Host-specific driving force in human immunodeficiency virus type 1 evolution in vivo. J Virol 71:2555-61
Kedes, D H; Operskalski, E; Busch, M et al. (1996) The seroepidemiology of human herpesvirus 8 (Kaposi's sarcoma-associated herpesvirus): distribution of infection in KS risk groups and evidence for sexual transmission. Nat Med 2:918-24
Faucett, C L; Thomas, D C (1996) Simultaneously modelling censored survival data and repeatedly measured covariates: a Gibbs sampling approach. Stat Med 15:1663-85
Diaz, R S; Sabino, E C; Mayer, A et al. (1996) Lack of dual HIV infection in a transfusion recipient exposed to two seropositive blood components. AIDS Res Hum Retroviruses 12:1291-5
Diaz, R S; Sabino, E C; Mayer, A et al. (1995) Dual human immunodeficiency virus type 1 infection and recombination in a dually exposed transfusion recipient. The Transfusion Safety Study Group. J Virol 69:3273-81
Wong, W Y; Powars, D R; Operskalski, E A et al. (1995) Blood transfusions and immunophenotypic alterations of lymphocyte subsets in sickle cell anemia. The Transfusion Safety Study Group. Blood 85:2091-7
Busch, M P; Valinsky, J E; Paglieroni, T et al. (1994) Screening of blood donors for idiopathic CD4+ T-lymphocytopenia. Transfusion 34:192-7
Mosley, J W; Nowicki, M J; Kasper, C K et al. (1994) Hepatitis A virus transmission by blood products in the United States. Transfusion Safety Study Group. Vox Sang 67 Suppl 1:24-8

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