The Cooperative Study of Sickle Cell Disease (CSSCD) is a multi-institutional, cooperative investigation conducted by the Sickle Cell Disease Branch, Division of Blood Diseases and Resources, National Heart, Lung, and Blood Institute. Thirty-nine hundred (3900) patients have been enrolled and are presently followed at twenty-three clinical sites (fifteen contracts). This contractor is responsible for coordinating and managing the comprehensive, detailed, and integrated database for this investigation. The overall management includes maintaining confidential data files, monitoring completion of study objectives and center performance, generating reports, providing data analysis, and participating in the publishing of the results.

National Institute of Health (NIH)
Division of Blood Diseases And Resources (NHLBI)
Research and Development Contracts (N01)
Project #
Application #
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of Illinois at Chicago
Public Health & Prev Medicine
Schools of Public Health
United States
Zip Code
Liu, Ching-Ti; Monda, Keri L; Taylor, Kira C et al. (2013) Genome-wide association of body fat distribution in African ancestry populations suggests new loci. PLoS Genet 9:e1003681
Musunuru, Kiran; Romaine, Simon P R; Lettre, Guillaume et al. (2012) Multi-ethnic analysis of lipid-associated loci: the NHLBI CARe project. PLoS One 7:e36473
Tin, Adrienne; Woodward, Owen M; Kao, Wen Hong Linda et al. (2011) Genome-wide association study for serum urate concentrations and gout among African Americans identifies genomic risk loci and a novel URAT1 loss-of-function allele. Hum Mol Genet 20:4056-68
Liu, Ching-Ti; Garnaas, Maija K; Tin, Adrienne et al. (2011) Genetic association for renal traits among participants of African ancestry reveals new loci for renal function. PLoS Genet 7:e1002264
Fox, Ervin R; Young, J Hunter; Li, Yali et al. (2011) Association of genetic variation with systolic and diastolic blood pressure among African Americans: the Candidate Gene Association Resource study. Hum Mol Genet 20:2273-84
Böger, Carsten A; Chen, Ming-Huei; Tin, Adrienne et al. (2011) CUBN is a gene locus for albuminuria. J Am Soc Nephrol 22:555-70
Zhu, Xiaofeng; Young, J H; Fox, Ervin et al. (2011) Combined admixture mapping and association analysis identifies a novel blood pressure genetic locus on 5p13: contributions from the CARe consortium. Hum Mol Genet 20:2285-95
Pasaniuc, Bogdan; Zaitlen, Noah; Lettre, Guillaume et al. (2011) Enhanced statistical tests for GWAS in admixed populations: assessment using African Americans from CARe and a Breast Cancer Consortium. PLoS Genet 7:e1001371
Musunuru, Kiran; Lettre, Guillaume; Young, Taylor et al. (2010) Candidate gene association resource (CARe): design, methods, and proof of concept. Circ Cardiovasc Genet 3:267-75
Marcus, Gregory M; Alonso, Alvaro; Peralta, Carmen A et al. (2010) European ancestry as a risk factor for atrial fibrillation in African Americans. Circulation 122:2009-15

Showing the most recent 10 out of 12 publications