Abstract

The major objective of this project is to develop, solicit and make available monoclonal antibodies of hybridomas relevant to limb development. The goal of the Developmental Studies Hybridoma Bank (DSHB) has been to build an easily accessible source of well-characterized products at reasonable cost through solicitation of existing hybridomas and through the development of new hybaridomas. The continuation to the project will expand the DSHB into other areas of development, including the human immune system.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research and Development Contracts (N01)
Project #
N01HD023144-001
Application #
2314877
Study Section
Project Start
1991-12-15
Project End
1996-10-31
Budget Start
1993-01-26
Budget End
1993-10-31
Support Year
Fiscal Year
1993
Total Cost
Indirect Cost

  Institution

Name
Johns Hopkins University
Department
Pharmacology
Type
Schools of Medicine
DUNS #
045911138
City
Baltimore
State
MD
Country
United States
Zip Code
21218

  Publications

Maguen, Ezra; Rabinowitz, Yaron S; Regev, Lee et al. (2008) Alterations of extracellular matrix components and proteinases in human corneal buttons with INTACS for post-laser in situ keratomileusis keratectasia and keratoconus. Cornea 27:565-73
Sun, Yunfu; Dykes, Iain M; Liang, Xingqun et al. (2008) A central role for Islet1 in sensory neuron development linking sensory and spinal gene regulatory programs. Nat Neurosci 11:1283-93
Fedtsova, Natalia; Quina, Lely A; Wang, Shirong et al. (2008) Regulation of the development of tectal neurons and their projections by transcription factors Brn3a and Pax7. Dev Biol 316:6-20
Coiffier, Delphine; Charroux, Bernard; Kerridge, Stephen (2008) Common functions of central and posterior Hox genes for the repression of head in the trunk of Drosophila. Development 135:291-300
Ijpenberg, A; Perez-Pomares, J M; Guadix, J A et al. (2007) Wt1 and retinoic acid signaling are essential for stellate cell development and liver morphogenesis. Dev Biol 312:157-70
Eucher, James N; Uemura, Etsuro; Sakaguchi, Donald S et al. (2007) Amyloid-beta peptide affects viability but not differentiation of embryonic and adult rat hippocampal progenitor cells. Exp Neurol 203:486-92
Guadix, Juan A; Carmona, Rita; Munoz-Chapuli, Ramon et al. (2006) In vivo and in vitro analysis of the vasculogenic potential of avian proepicardial and epicardial cells. Dev Dyn 235:1014-26
Perez-Pomares, Jose M; Mironov, V; Guadix, Juan A et al. (2006) In vitro self-assembly of proepicardial cell aggregates: an embryonic vasculogenic model for vascular tissue engineering. Anat Rec A Discov Mol Cell Evol Biol 288:700-13
Fujita, Manabu; Khazenzon, Natalya M; Bose, Shikha et al. (2005) Overexpression of beta1-chain-containing laminins in capillary basement membranes of human breast cancer and its metastases. Breast Cancer Res 7:R411-21
Brazel, C Y; Nunez, J L; Yang, Z et al. (2005) Glutamate enhances survival and proliferation of neural progenitors derived from the subventricular zone. Neuroscience 131:55-65

Showing the most recent 10 out of 204 publications