Perform a retrospective cohort study of the risk of gallbladder and other hepatobiliary diseases related to the use of oral contraceptives. Using data from the Walnut Creek Contraceptive Drug Study, supplemented with data to be obtained from review of the Kaiser Permanente Medical Care Program records, a comparison will be made of women who have been exposed to steroid contraceptives on the occurrence of hepatobiliary disease in women. The contribution of length and cumulative level of estrogen/progestin exposure to the risk of these diseases will be quantified.

Project Start
1984-06-15
Project End
1986-06-14
Budget Start
1985-06-28
Budget End
1986-06-14
Support Year
Fiscal Year
1985
Total Cost
Indirect Cost
Name
Kaiser Foundation Research Institute
Department
Type
DUNS #
City
Oakland
State
CA
Country
United States
Zip Code
94612
Petitti, D B; Sidney, S (1988) Obesity and cholecystectomy among women: implications for prevention. Am J Prev Med 4:327-30
Hahn, R C; Petitti, D B (1988) Minnesota Multiphasic Personality Inventory-rated depression and the incidence of breast cancer. Cancer 61:845-8
Petitti, D B; Sidney, S; Perlman, J A (1988) Increased risk of cholecystectomy in users of supplemental estrogen. Gastroenterology 94:91-5
Petitti, D B; Perlman, J A; Sidney, S (1987) Noncontraceptive estrogens and mortality: long-term follow-up of women in the Walnut Creek Study. Obstet Gynecol 70:289-93