Abstract

The Contractor shall perform a population-based case-control study on the risk of rheumatoid arthritis in oral contraceptive users.
The aims of the project are to determine whether exposure to specific contraceptive steroids, currently or in the past, reduce the current or lifetime risk of developing rheumatoid arthritis. Sub-analyses will be undertaken to clarify the nature of the association according to characteristics of hormone exposure, such as duration of steroid use or cumulative dose of estrogen or specific progestins. Where possible, special sub-groups of women at particularly high risk will be identified.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research and Development Contracts (N01)
Project #
N01HD062914-008
Application #
2315834
Study Section
Project Start
1986-05-15
Project End
1993-05-14
Budget Start
1992-09-24
Budget End
1993-05-14
Support Year
Fiscal Year
1992
Total Cost
Indirect Cost

  Institution

Name
University of Washington
Department
Public Health & Prev Medicine
Type
Schools of Public Health
DUNS #
135646524
City
Seattle
State
WA
Country
United States
Zip Code
98195

  Publications

Ma, Kimberly K; Nelson, J Lee; Guthrie, Katherine A et al. (2014) Adverse pregnancy outcomes and risk of subsequent rheumatoid arthritis. Arthritis Rheumatol 66:508-12
Guthrie, Katherine A; Dugowson, Carin E; Voigt, Lynda F et al. (2010) Does pregnancy provide vaccine-like protection against rheumatoid arthritis? Arthritis Rheum 62:1842-8
Voigt, Lynda F; Koepsell, Thomas D; Daling, Janet R (2003) Characteristics of telephone survey respondents according to willingness to participate. Am J Epidemiol 157:66-73
Shapiro, J A; Koepsell, T D; Voigt, L F et al. (1996) Diet and rheumatoid arthritis in women: a possible protective effect of fish consumption. Epidemiology 7:256-63
Nelson, J L; Dugowson, C E; Koepsell, T D et al. (1994) Rheumatoid factor, HLA-DR4, and allelic variants of DRB1 in women with recent-onset rheumatoid arthritis. Arthritis Rheum 37:673-80
Voigt, L F; Koepsell, T D; Nelson, J L et al. (1994) Smoking, obesity, alcohol consumption, and the risk of rheumatoid arthritis. Epidemiology 5:525-32
Koepsell, T D; Dugowson, C E; Nelson, J L et al. (1994) Non-contraceptive hormones and the risk of rheumatoid arthritis in menopausal women. Int J Epidemiol 23:1248-55
Dugowson, C E; Koepsell, T D; Voigt, L F et al. (1991) Rheumatoid arthritis in women. Incidence rates in group health cooperative, Seattle, Washington, 1987-1989. Arthritis Rheum 34:1502-7
Dugowson, C E; Nelson, J L; Koepsell, T D (1990) Evaluation of the 1987 revised criteria for rheumatoid arthritis in a cohort of newly diagnosed female patients. Arthritis Rheum 33:1042-6