Abstract

The purpose of this laboratory contract is to measure the level of caffeine and its primary metabolite. paraxanthine, in approximately 6,500 serum samples that have been stored in the Collaborative Perinatal Project serum repository, as well as to measure osmolality in each of these samples and toinine in approximately 565 of these samples.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research and Development Contracts (N01)
Project #
N01HD073262-002
Application #
2885460
Study Section
Project Start
1996-11-01
Project End
1998-12-31
Budget Start
1998-10-21
Budget End
1998-12-31
Support Year
Fiscal Year
1999
Total Cost
Indirect Cost

  Institution

Name
University of Utah
Department
Pharmacology
Type
Schools of Pharmacy
DUNS #
City
Salt Lake City
State
UT
Country
United States
Zip Code
84112

  Publications

Klebanoff, Mark A; Zhang, Jun; Zhang, Cuilin et al. (2009) Maternal serum theobromine and the development of preeclampsia. Epidemiology 20:727-32
Klebanoff, Mark A; Levine, Richard J; Clemens, John D et al. (2002) Maternal serum caffeine metabolites and small-for-gestational age birth. Am J Epidemiol 155:32-7
Klebanoff, M A; Levine, R J; DerSimonian, R et al. (1999) Maternal serum paraxanthine, a caffeine metabolite, and the risk of spontaneous abortion. N Engl J Med 341:1639-44
Klebanoff, M A; Levine, R J; Clemens, J D et al. (1998) Serum cotinine concentration and self-reported smoking during pregnancy. Am J Epidemiol 148:259-62