Pulmonary Complications of Htlv-III/Lav (HIV) Infection

Poole, Kenneth W.

Abstract

The overall objective of this contract is to establish a clinical coordinating center (CCC) to provide statistical and coordination services for the proposed multi-center study to determine the pulmonary complications of HTLV-III/LAV infection. Basically, the CCC will be involved in all aspects of the proposed study including (1) the development of the protocol, manual of operations, data forms, and quality assurance procedures, (2) the development and the implementation of procedures for the conversion of data to the CCC computer, and (3) the processing of data including statistical analysis, final report preparation for the study, and publication of the study data. The CCC will also provide other services such as assistance in arranging and planning Steering Committee meetings, including preparation and distribution of the minutes and the reproduction and distribution of study documents.

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: Division of Lung Diseases (NHLBI)
• Type: Research and Development Contracts (N01)
• Project #: N01HR076029-002
• Application #: 3657589
• Project Start: 1987-09-30
• Project End: 1992-09-29
• Budget Start: 1989-06-30
• Budget End: 1990-09-15
• Fiscal Year: 1989

Institution

• Name: Research Triangle Institute
• DUNS #: 131606022
• City: Research Triangle Park
• State: NC
• Country: United States
• Zip Code: 27709

Publications

Morris, A M; Huang, L; Bacchetti, P et al. (2000) Permanent declines in pulmonary function following pneumonia in human immunodeficiency virus-infected persons. The Pulmonary Complications of HIV Infection Study Group. Am J Respir Crit Care Med 162:612-6

Osmond, D H; Chin, D P; Glassroth, J et al. (1999) Impact of bacterial pneumonia and Pneumocystis carinii pneumonia on human immunodeficiency virus disease progression. Pulmonary Complications of HIV Study Group. Clin Infect Dis 29:536-43

Huang, L; Stansell, J; Osmond, D et al. (1999) Performance of an algorithm to detect Pneumocystis carinii pneumonia in symptomatic HIV-infected persons. Pulmonary Complications of HIV Infection Study Group. Chest 115:1025-32

Wallace, J M; Lim, R; Browdy, B L et al. (1998) Risk factors and outcomes associated with identification of Aspergillus in respiratory specimens from persons with HIV disease. Pulmonary Complications of HIV Infection Study Group. Chest 114:131-7

Wallace, J M; Hansen, N I; Lavange, L et al. (1997) Respiratory disease trends in the Pulmonary Complications of HIV Infection Study cohort. Pulmonary Complications of HIV Infection Study Group. Am J Respir Crit Care Med 155:72-80

Wallace, J M; Stone, G S; Browdy, B L et al. (1997) Nonspecific airway hyperresponsiveness in HIV disease. Pulmonary Complications of HIV Infection Study Group. Chest 111:121-7

Chin, D P; Osmond, D; Page-Shafer, K et al. (1996) Reliability of anergy skin testing in persons with HIV infection. The pulmonary Complications of HIV Infection Study Group. Am J Respir Crit Care Med 153:1982-4

Hirschtick, R E; Glassroth, J; Jordan, M C et al. (1995) Bacterial pneumonia in persons infected with the human immunodeficiency virus. Pulmonary Complications of HIV Infection Study Group. N Engl J Med 333:845-51

Glassroth, J; Jordan, M; Wallace, J M et al. (1994) Use of preventive interventions by persons infected with type-1 human immunodeficiency virus (HIV-1). The Pulmonary Complications of HIV Study Group. Am J Prev Med 10:259-66

Markowitz, N; Hansen, N I; Wilcosky, T C et al. (1993) Tuberculin and anergy testing in HIV-seropositive and HIV-seronegative persons. Pulmonary Complications of HIV Infection Study Group. Ann Intern Med 119:185-93