Clin Ctr Clin Trial/Observational Study of Whi

Black, Henry R.

Abstract

The objectives of each Clinical Center are to cooperate with the Clinical Coordinating Center in implementing the overall Women's Health Initiative Clinical Trial and Observational study. The Clinical Centers will join the sixteen Vanguard Clinical Centers in recruiting a group of postmenopausal U.S. women age 50-79, randomize them to a number of interventions, ensure adherence and adequate follow-up, and collect and transmit data and biological samples as needed for the ascertainment of the outcomes of the CT/OS. Each Clinical Center shall recruit 1,400 to the CT and 2,220 women to the OS.

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: Women'S Health Initiative - Office of The Director Nih (WH)
• Type: Research and Development Contracts (N01)
• Project #: N01WH042124-000
• Application #: 2326766
• Project Start: 1994-09-30
• Project End: 2005-09-14
• Budget Start: 1994-09-30
• Budget End: 1997-06-22
• Fiscal Year: 1994

Institution

• Name: Rush University Medical Center
• City: Chicago
• State: IL
• Country: United States
• Zip Code: 60612

Publications

Gong, J; Nishimura, K K; Fernandez-Rhodes, L et al. (2018) Trans-ethnic analysis of metabochip data identifies two new loci associated with BMI. Int J Obes (Lond) 42:384-390

Kato, Ikuko; Lane, Dorothy; Womack, Catherine R et al. (2017) Interaction between Nonsteroidal Anti-inflammatory Drugs and Low-fat Dietary Intervention on Colorectal Cancer Incidence; the Women's Health Initiative (WHI) Dietary Modification Trial. J Am Coll Nutr 36:462-469

Zaslavsky, Oleg; Woods, Nancy F; LaCroix, Andrea Z et al. (2016) Identification of Risk Factors for Mortality and Poor-Quality-of-Life Survival in Frail Older Women Participating in the Women's Health Initiative Observational Study. J Am Geriatr Soc 64:831-7

Klimentidis, Y C; Arora, A; Chougule, A et al. (2016) FTO association and interaction with time spent sitting. Int J Obes (Lond) 40:411-6

Gangwisch, James E; Hale, Lauren; Garcia, Lorena et al. (2015) High glycemic index diet as a risk factor for depression: analyses from the Women's Health Initiative. Am J Clin Nutr 102:454-63

Salmoirago-Blotcher, Elena; Hovey, Kathleen M; Andrews, Christopher A et al. (2015) Statin use and risk of haemorrhagic stroke in a community-based cohort of postmenopausal women: an observational study from the Women's Health Initiative. BMJ Open 5:e007075

Kato, Ikuko; Young, Alicia; Liu, Jingmin et al. (2015) Electric Blanket Use and Risk of Thyroid Cancer in the Women's Health Initiative Observational Cohort. Women Health 55:829-41

Jacobs, Eric J; Newton, Christina C; Carter, Brian D et al. (2015) What proportion of cancer deaths in the contemporary United States is attributable to cigarette smoking? Ann Epidemiol 25:179-182.e1

Roberts, Angharad M; Ware, James S; Herman, Daniel S et al. (2015) Integrated allelic, transcriptional, and phenomic dissection of the cardiac effects of titin truncations in health and disease. Sci Transl Med 7:270ra6

Chlebowski, Rowan T; Aragaki, Aaron K; Anderson, Garnet L (2015) Menopausal Hormone Therapy Influence on Breast Cancer Outcomes in the Women's Health Initiative. J Natl Compr Canc Netw 13:917-24