Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Program Projects (P01)
Project #
5P01AG009017-05
Application #
2050548
Study Section
Aging Review Committee (AGE)
Project Start
1990-05-01
Project End
1997-04-30
Budget Start
1994-05-01
Budget End
1997-04-30
Support Year
5
Fiscal Year
1994
Total Cost
Indirect Cost
Name
Institute for Basic Research in Dev Disabil
Department
Type
DUNS #
167205090
City
Staten Island
State
NY
Country
United States
Zip Code
10314
Ye, Xuemin; Meeker, Harry C; Kozlowski, Piotr et al. (2004) The occurrence of vacuolation, and periodic acid-Schiff (PAS)-positive granules and plaques in the brains of C57BL/6J, AKR, senescence-prone (SAMP8) and senescence-resistant (SAMR1) mice infected with various scrapie strains. Brain Res 995:158-66
Ye, X; Carp, R I; Schmued, L C et al. (2001) Fluoro-Jade and silver methods: application to the neuropathology of scrapie, a transmissible spongiform encephalopathy. Brain Res Brain Res Protoc 8:104-12
Ye, X; Scallet, A; Carp, R I (1999) Abnormal periodic acid-Schiff (PAS)-positive substance in the islets of Langerhans, pituitaries and adrenal glands of 139H scrapie-infected hamsters. Histol Histopathol 14:673-8
Carp, R I; Meeker, H C; Caruso, V et al. (1999) Scrapie strain-specific interactions with endogenous murine leukaemia virus. J Gen Virol 80 ( Pt 1):5-10
Ye, X; Scallet, A C; Kascsak, R J et al. (1998) Astrocytosis and amyloid deposition in scrapie-infected hamsters. Brain Res 809:277-87
Carp, R I; Meeker, H; Sersen, E et al. (1998) Analysis of the incubation periods, induction of obesity and histopathological changes in senescence-prone and senescence-resistant mice infected with various scrapie strains. J Gen Virol 79 ( Pt 11):2863-9
Meeker, H C; Carp, R I (1997) Titers of murine leukemia virus are higher in brains of SAMP8 than SAMR1 mice. Neurobiol Aging 18:543-7
Carp, R I; Meeker, H; Sersen, E (1997) Scrapie strains retain their distinctive characteristics following passages of homogenates from different brain regions and spleen. J Gen Virol 78 ( Pt 1):283-90
Ye, X; Carp, R I (1996) Margination and diapedesis of inflammatory cells in the islets of Langerhans in hamsters infected with the 139H strain of scrapie. J Comp Pathol 114:149-63
Ye, X; Carp, R I (1996) Histopathological changes in the islets of Langerhans in hamsters infected with the 139H strain of scrapie: semi-thin section study. Histol Histopathol 11:161-70

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