Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Program Projects (P01)
Project #
5P01AI035125-04
Application #
2070551
Study Section
Special Emphasis Panel (SRC (23))
Project Start
1993-09-30
Project End
1997-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Stanford University
Department
Pediatrics
Type
Schools of Medicine
DUNS #
800771545
City
Stanford
State
CA
Country
United States
Zip Code
94305
Boytim, M L; Lilly, P; Drouvalakis, K et al. (2000) A human class II MHC-derived peptide antagonizes phosphatidylinositol 3-kinase to block IL-2 signaling. J Clin Invest 105:1447-53
Boytim, M L; Lyu, S C; Jung, R et al. (1998) Inhibition of cell cycle progression by a synthetic peptide corresponding to residues 65-79 of an HLA class II sequence: functional similarities but mechanistic differences with the immunosuppressive drug rapamycin. J Immunol 160:2215-22
Pattison, J M; Krensky, A M (1997) New insights into mechanisms of allograft rejection. Am J Med Sci 313:257-63
Krensky, A M; Clayberger, C (1996) Structure of HLA molecules and immunosuppressive effects of HLA derived peptides. Int Rev Immunol 13:173-85
Nossner, E; Goldberg, J E; Naftzger, C et al. (1996) HLA-derived peptides which inhibit T cell function bind to members of the heat-shock protein 70 family. J Exp Med 183:339-48
Krensky, A M; Clayberger, C (1995) Human leukocyte antigen-derived peptides as novel immunosuppressives. Proc Assoc Am Physicians 107:81-5
Krensky, A M; Clayberger, C (1994) Transplantation immunology. Pediatr Clin North Am 41:819-39
Nisco, S; Vriens, P; Hoyt, G et al. (1994) Induction of allograft tolerance in rats by an HLA class-I-derived peptide and cyclosporine A. J Immunol 152:3786-92