The Immunomicroscopy Core will consist of a state-of- the-art fluorescence imaging unit, a laser dissection microscope system, and equipment for preparing specimens including a cryostat and microtome. It will be supervised by the director, who will be responsible for training the senior research assistant and assuring its quality control. The Core will be used to define immune responses to Francisella tulerensis infection with time, as well as aid in the discovery of molecules involved in virulence such as sensitivity to intramacrophage survival and resistance to antimicrobial peptides. Analyses will be done in situ with tissues as well as at the level of single cells. As such, it will play a critical role in successfully completing the long-term goals of this Program Project: Tularemia: Pathogenesis and Host Response

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Program Projects (P01)
Project #
5P01AI057986-02
Application #
7310218
Study Section
Special Emphasis Panel (ZAI1)
Project Start
Project End
Budget Start
2006-07-01
Budget End
2007-06-30
Support Year
2
Fiscal Year
2006
Total Cost
$84,399
Indirect Cost
Name
University of Texas Health Science Center San Antonio
Department
Type
DUNS #
800189185
City
San Antonio
State
TX
Country
United States
Zip Code
78249
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