Project Start
Project End
Budget Start
Budget End
Support Year
18
Fiscal Year
1985
Total Cost
Indirect Cost
Name
Massachusetts General Hospital
Department
Type
DUNS #
City
Boston
State
MA
Country
United States
Zip Code
Hustmyer, F G; Schipani, E; Peacock, M (1993) BsmI polymorphism at the parathyroid hormone receptor locus (PTHR) in three populations. Hum Mol Genet 2:1330
Bringhurst, F R; Juppner, H; Guo, J et al. (1993) Cloned, stably expressed parathyroid hormone (PTH)/PTH-related peptide receptors activate multiple messenger signals and biological responses in LLC-PK1 kidney cells. Endocrinology 132:2090-8
Fukayama, S; Tashjian Jr, A H; Bringhurst, F R (1993) Role of protein kinase A in the regulation of cytosolic free calcium in human osteoblast-like SaOS-2 cells. Am J Physiol 264:C464-70
Fukayama, S; Tashjian Jr, A H; Bringhurst, F R (1992) Mechanisms of desensitization to parathyroid hormone in human osteoblast-like SaOS-2 cells. Endocrinology 131:1757-69
Fukayama, S; Tashjian Jr, A H; Bringhurst, F R (1992) Forskolin-induced homologous desensitization via an adenosine 3',5'-monophosphate-dependent mechanism(s) in human osteoblast-like SaOS-2 cells. Endocrinology 131:1770-6
Fukayama, S; Kearns, A K; Skurat, R M et al. (1991) Protein kinase A-dependent inhibition of alkaline phosphatase release by SaOS-2 human osteoblastic cells: studies in new mutant cell lines that express a cyclic AMP-resistant phenotype. Cell Regul 2:889-96
Bringhurst, F R; Stern, A M; Yotts, M et al. (1989) Peripheral metabolism of [35S]parathyroid hormone in vivo: influence of alterations in calcium availability and parathyroid status. J Endocrinol 122:237-45
Yamamoto, I; Potts Jr, J T; Segre, G V (1988) Glucocorticoids increase parathyroid hormone receptors in rat osteoblastic osteosarcoma cells (ROS 17/2). J Bone Miner Res 3:707-12
Juppner, H; Abou-Samra, A B; Uneno, S et al. (1988) The parathyroid hormone-like peptide associated with humoral hypercalcemia of malignancy and parathyroid hormone bind to the same receptor on the plasma membrane of ROS 17/2.8 cells. J Biol Chem 263:8557-60
Bringhurst, F R; Stern, A M; Yotts, M et al. (1988) Peripheral metabolism of PTH: fate of biologically active amino terminus in vivo. Am J Physiol 255:E886-93

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