This project examines the functional and biomechanical effects of tracheostomy on swallow in head and neck surgical patients who are about to be decannulated. Since many surgically treated head and neck cancer patients receive a tracheostomy at some point in their care, as do patients with various respiratory diseases, spinal cord injuries, and other neurologic disorders, and there is little quantified information and great divergence of clinical opinion regarding the effects of tracheostomy, this project proposes to examine and quantify the systematic effects of tracheostomy in particular types of head and neck surgical patients with tracheostomy who are about to be decannulated. Swallowing function of 40 head and neck cancer patients with tracheostomy who are about to be decannulated will be studied with simultaneous videofluoroscopy and endoscopy with the tracheostomy in place and after decannulation. Another 40 head and neck cancer patients will be studied with simultaneous pharyngeal manometry and videofluoroscopy. We hypothesize that tracheostomy changes the biomechanics of swallow, particularly laryngeal evaluation and anterior movement, laryngeal closure and cricopharyngeal opening. By comparing the biomechanical and pressure characteristics of swallow, bolus transit measures, and vocal fold movement patterns in these groups, we will be able to define any systematic effects of tracheostomy and the interaction of a tracheostomy with particular swallowing disorders and head and neck surgical procedures.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Program Projects (P01)
Project #
5P01CA040007-07
Application #
3795026
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
7
Fiscal Year
1992
Total Cost
Indirect Cost
Name
Northwestern University at Chicago
Department
Type
DUNS #
City
Evanston
State
IL
Country
United States
Zip Code
60201
Logemann, Jerilyn A (2014) Critical Factors in the Oral Control Needed for Chewing and Swallowing. J Texture Stud 45:173-179
Pauloski, Barbara Roa; Logemann, Jerilyn A; Rademaker, Alfred W et al. (2013) Effects of enhanced bolus flavors on oropharyngeal swallow in patients treated for head and neck cancer. Head Neck 35:1124-31
Pauloski, Barbara Roa; Rademaker, Alfred W; Lazarus, Cathy et al. (2009) Relationship between manometric and videofluoroscopic measures of swallow function in healthy adults and patients treated for head and neck cancer with various modalities. Dysphagia 24:196-203
Logemann, Jeri A; Pauloski, Barbara Roa; Rademaker, Alfred W et al. (2008) Swallowing disorders in the first year after radiation and chemoradiation. Head Neck 30:148-58
Pauloski, Barbara Roa; Rademaker, Alfred W; Logemann, Jerilyn A et al. (2006) Relationship between swallow motility disorders on videofluorography and oral intake in patients treated for head and neck cancer with radiotherapy with or without chemotherapy. Head Neck 28:1069-76
Daggett, Alicia; Logemann, Jeri; Rademaker, Alfred et al. (2006) Laryngeal penetration during deglutition in normal subjects of various ages. Dysphagia 21:270-4
Smith, Christina H; Logemann, Jeri A; Burghardt, Wesley R et al. (2006) Oral and oropharyngeal perceptions of fluid viscosity across the age span. Dysphagia 21:209-17
Logemann, Jeri A; Rademaker, Alfred W; Pauloski, Barbara Roa et al. (2006) Site of disease and treatment protocol as correlates of swallowing function in patients with head and neck cancer treated with chemoradiation. Head Neck 28:64-73
Logemann, Jeri A; Williams, Rohan B; Rademaker, Alfred et al. (2005) The relationship between observations and measures of oral and pharyngeal residue from videofluorography and scintigraphy. Dysphagia 20:226-31
List, Marcy A; Rutherford, Judith Lee; Stracks, John et al. (2004) Prioritizing treatment outcomes: head and neck cancer patients versus nonpatients. Head Neck 26:163-70

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