Objective: The continuing goal of the Basic Microbiology and Infectious Disease (BMID) training program is to augment the training of outstanding predoctoral students in the areas of microbiology and infectious disease and to prepare them for exceptional and productive careers in biomedical research. Rationale and Need for the BMID: Infectious disease continues to have a major impact on human health and there is a growing need for well-trained and highly skilled researchers to study mechanisms of pathogenesis and to develop new methods of detection, treatment, and prevention. History and Leadership of the BMID Program: The BMID is entering its 42nd year at the University of Florida. Dr. David Bloom has been PD/PI since 2002 and has been assisted by Associate Director, Dr. Stephanie Karst, since 2016. The program is guided by an Internal Advisory Board as well as an External Advisory Board who visit annually for a site visit and Mini-Symposium and provide program evaluation. Design of the Program: The overarching goals of the program design are to: 1) expose our trainees to research on infectious disease from the combined perspective of clinical and basic sciences and 2) provide microbiology and infectious disease-centric professional development and career guidance to enhance future success. Research Areas and Faculty Composition: Seventeen faculty preceptors come from 4 colleges and 7 departments/divisions. Composition: 10 male, 7 female; 11 Professors, 4 Associate and 2 Assistant Professors; 6 bacteriologists; 6 virologists; 1 parasitologist and 4 infection-related immunologists. Institutional Support: UF provides specifically for the BMID: 1) 0.1 FTE for the PI/PD; 0.3 FTE for a program assistant; support for internships, seminars, professional development roundtables, summer internships for graduate and minority recruiting. Training Level and Duration of Training: We are requesting 6 predoctoral training positions. Trainees are generally appointed after their second year (after entering candidacy) for 2 years of support. BMID-specific Training Components: Combined Microbiology & Infectious Disease Case Conferences; Distinguished Lectures in Microbiology and Infectious Disease Seminar Series; Professional Development Meetings; Career Roundtables; Internship program; and Training in Responsible Conduct and Ethics. Progress: Over the last 20 years: 92% of trainees have graduated with a Ph.D.; 82% of those are in research- related careers and the remaining 18% are in medically-related careers. During the last 5 years, out of 15 trainees appointed, the composition: 8 females (53%) and 7 (47%) males; 3 (20%) URMs. Proposed New Components: Leadership Development Workshop and Summer Research Internships Internships in Microbiology (SRIMP) for recruiting top undergraduates to UF (and the BMID).

Public Health Relevance

Infectious disease is a pervasive problem in human heath. The continuing goal of this training program in Basic Microbiology and Infectious Disease is to provide exceptional training in the mechanisms of infectious disease that bridges the gap between basic and clinical science. This will help enhance the quality of the biomedical research workforce in the United States.

National Institute of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
Institutional National Research Service Award (T32)
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Microbiology and Infectious Diseases B Subcommittee (MID)
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Coomes, Stephanie
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University of Florida
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United States
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Kim, Wan-Ju; Shea, Allyson E; Kim, Joon-Hyung et al. (2018) Uropathogenic Escherichia coli invades bladder epithelial cells by activating kinase networks in host cells. J Biol Chem 293:16518-16527
Moore, Brenda D; Martin, Jason; de Mena, Lorena et al. (2018) Short A? peptides attenuate A?42 toxicity in vivo. J Exp Med 215:283-301
Lorentsen, Kyle J; Cho, Jonathan J; Luo, Xiaoping et al. (2018) Bcl11b is essential for licensing Th2 differentiation during helminth infection and allergic asthma. Nat Commun 9:1679
Ilyas, Maria; Mietzsch, Mario; Kailasan, Shweta et al. (2018) Atomic Resolution Structures of Human Bufaviruses Determined by Cryo-Electron Microscopy. Viruses 10:
Marr, Matthew; D'Abramo, Anthony; Pittman, Nikea et al. (2018) Optimizing the Targeting of Mouse Parvovirus 1 to Murine Melanoma Selects for Recombinant Genomes and Novel Mutations in the Viral Capsid Gene. Viruses 10:
Pittman, Nikéa; Misseldine, Adam; Geilen, Lorena et al. (2017) Atomic Resolution Structure of the Oncolytic Parvovirus LuIII by Electron Microscopy and 3D Image Reconstruction. Viruses 9:
Ortega, M Sofia; Kurian, Justin J; McKenna, Robert et al. (2017) Characteristics of candidate genes associated with embryonic development in the cow: Evidence for a role for WBP1 in development to the blastocyst stage. PLoS One 12:e0178041
Rogers, Geoffrey L; Shirley, Jamie L; Zolotukhin, Irene et al. (2017) Plasmacytoid and conventional dendritic cells cooperate in crosspriming AAV capsid-specific CD8+ T cells. Blood 129:3184-3195
Cho, Jonathan J; Stewart, Joshua M; Drashansky, Theodore T et al. (2017) An antigen-specific semi-therapeutic treatment with local delivery of tolerogenic factors through a dual-sized microparticle system blocks experimental autoimmune encephalomyelitis. Biomaterials 143:79-92
Grau, Katrina R; Roth, Alexa N; Zhu, Shu et al. (2017) The major targets of acute norovirus infection are immune cells in the gut-associated lymphoid tissue. Nat Microbiol 2:1586-1591

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