Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Program Projects (P01)
Project #
5P01CA051083-02
Application #
3094447
Study Section
Special Emphasis Panel (SRC (F2))
Project Start
1992-09-25
Project End
1997-06-30
Budget Start
1993-07-01
Budget End
1994-06-30
Support Year
2
Fiscal Year
1993
Total Cost
Indirect Cost
Name
Thomas Jefferson University
Department
Type
Schools of Medicine
DUNS #
061197161
City
Philadelphia
State
PA
Country
United States
Zip Code
19107
Ishii, H; Dumon, K R; Vecchione, A et al. (2001) Effect of adenoviral transduction of the fragile histidine triad gene into esophageal cancer cells. Cancer Res 61:1578-84
Ishii, H; Vecchione, A; Murakumo, Y et al. (2001) FEZ1/LZTS1 gene at 8p22 suppresses cancer cell growth and regulates mitosis. Proc Natl Acad Sci U S A 98:10374-9
Vecchione, A; Zanesi, N; Trombetta, G et al. (2001) Cervical dysplasia, ploidy, and human papillomavirus status correlate with loss of Fhit expression. Clin Cancer Res 7:1306-12
Murakumo, Y; Roth, T; Ishii, H et al. (2000) A human REV7 homolog that interacts with the polymerase zeta catalytic subunit hREV3 and the spindle assembly checkpoint protein hMAD2. J Biol Chem 275:4391-7
Pekarsky, Y; Hallas, C; Isobe, M et al. (1999) Abnormalities at 14q32.1 in T cell malignancies involve two oncogenes. Proc Natl Acad Sci U S A 96:2949-51
Zou, J P; Hirose, Y; Siddique, H et al. (1999) Structure and expression of variant BRCA2a lacking the transactivation domain. Oncol Rep 6:437-40
Numata, S; Claudio, P P; Dean, C et al. (1999) Bdp, a new member of a family of DNA-binding proteins, associates with the retinoblastoma gene product. Cancer Res 59:3741-7
Ishii, H; Baffa, R; Numata, S I et al. (1999) The FEZ1 gene at chromosome 8p22 encodes a leucine-zipper protein, and its expression is altered in multiple human tumors. Proc Natl Acad Sci U S A 96:3928-33
Pekarsky, Y; Campiglio, M; Siprashvili, Z et al. (1998) Nitrilase and Fhit homologs are encoded as fusion proteins in Drosophila melanogaster and Caenorhabditis elegans. Proc Natl Acad Sci U S A 95:8744-9
Huebner, K; Garrison, P N; Barnes, L D et al. (1998) The role of the FHIT/FRA3B locus in cancer. Annu Rev Genet 32:7-31

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