(Sea instructions): Project 2: Late Stage Lung Cancer focuses on Stages Illb-IV unresectable lung cancer within a program project with central themes related to palliative care, quality of life (QOL), and symptom management. This project focuses on Late Stage Lung Cancer, a population who have decreased survival and high QOL and symptom concerns.
The aims of the research are:
Aim1 : Test the effects of the Palliative Care Intervention (PCI) on overall QOL and psychological distress for patients with Late (Stage Illb-IV) non-resectable NSCLC compared to a group receiving usual care.
Aim 2 : Compare symptom control in the PCI group versus the usual care group in Late Stage NSCLC.
Aim 3 : Compare geriatric assessment outcomes (OARS Instrumental Activities of Daily Living, MOS Activities of Daily Living, MOS Social Activities Limitation Scale, Hospital Anxiety and Depression Scale scores, and the Karnofsky Performance Scale) in the PCI group versus the usual care group.
Aim 4 : Test the effects of the PCI on resource use as compared to the usual care group.
Aim 5 : Identify subgroups of patients who benefit most from the PCI in relation to sociodemographic characteristics, treatment factors, and geriatric assessment predictors at the 12 week primary end point. A two-group, prospective sequential, quasi-experimental, tandem enrollment design (N=326) will be used for this project, in which the usual care group is accrued and followed during Phase 1 and the intervention group is accrued and followed during Phase 2. The proposed PCI intervention combines pre-treatment assessment and goal setting through the collaboration of an interdisciplinary team. The Palliative Care Intervention is based on pilot work completed from 2005-2007 by the investigators documenting needs of lung cancer patients and testing the intervention. This project has great significance to public health given the significant numbers of people diagnosed with lung cancer and the associated individual and societal costs.
Lung cancer impacts elderly patients, creates extensive family and social burden and both psychosocial and financial consequences are substantial. Integration of palliative care into late stage lung cancer care can serve as a public health model to maximize both quality of life and health care resources.
|Kim, Jae Y; Sun, Virginia; Raz, Dan J et al. (2016) The impact of lung cancer surgery on quality of life trajectories in patients and family caregivers. Lung Cancer 101:35-39|
|Raz, Dan J; Sun, Virginia; Kim, Jae Y et al. (2016) Long-Term Effect of an Interdisciplinary Supportive Care Intervention for Lung Cancer Survivors After Surgical Procedures. Ann Thorac Surg 101:495-502; discussion 502-3|
|Ferrell, Betty; Sun, Virginia; Hurria, Arti et al. (2015) Interdisciplinary Palliative Care for Patients With Lung Cancer. J Pain Symptom Manage 50:758-67|
|Tiep, Brian; Sun, Virginia; Koczywas, Marianna et al. (2015) Pulmonary Rehabilitation and Palliative Care for the Lung Cancer Patient. J Hosp Palliat Nurs 17:462-468|
|Borneman, Tami; Sun, Virginia; Williams, Anna Cathy et al. (2015) Support for Patients and Family Caregivers in Lung Cancer: Educational Components of an Interdisciplinary Palliative Care Intervention. J Hosp Palliat Nurs 17:309-318|
|Gajra, Ajeet; Klepin, Heidi D; Feng, Tao et al. (2015) Predictors of chemotherapy dose reduction at first cycle in patients age 65 years and older with solid tumors. J Geriatr Oncol 6:133-40|
|Fujinami, Rebecca; Sun, Virginia; Zachariah, Finly et al. (2015) Family caregivers' distress levels related to quality of life, burden, and preparedness. Psychooncology 24:54-62|
|Sun, Virginia; Grant, Marcia; Koczywas, Marianna et al. (2015) Effectiveness of an interdisciplinary palliative care intervention for family caregivers in lung cancer. Cancer 121:3737-45|
|Sun, Virginia; Kim, Jae Y; Williams, Anna Cathy et al. (2014) Quality of life and symptoms following stereotactic body radiotherapy in early-stage lung cancer patients. J Community Support Oncol 12:407-414|
|Kernstine, Kemp H; Moon, James; Kraut, Michael J et al. (2014) Trimodality therapy for superior sulcus non-small cell lung cancer: Southwest Oncology Group-Intergroup Trial S0220. Ann Thorac Surg 98:402-10|
Showing the most recent 10 out of 21 publications