? Administrative Core The Administrative Core of the ?Program on Genetic and Dietary Predictors of Drug Response in Rural and AI/AN Populations? provides operational support to the three Projects and the Partnership Core, assuring coordination and communication for a complex multi-site Research Program. This program is based in a research partnership comprising the Universities of Washington, Montana, and Alaska (Fairbanks); Group Health Research Institute; and three tribal organizations, Southcentral Foundation (Anchorage, AK), the Confederated Salish and Kootenai Tribes (Flathead Reservation, MT), and the Yukon-Kuskokwim Health Corporation (Bethel, AK). The Administrative Core ensures the coordination of research effort within and between the different Projects and Cores; allocates NIH funds to assure the financial resources needed by the Project teams to execute their proposed specific aims, including reallocation of funds and effort, as needed to maximize the success of the entire Program; and provides fiduciary oversight for the expenditure of those funds. The administrative core is also the main liaison between the Program team, the research performance sites and NIH. Finally, the administrative core for this Research Program works with all participating sites to assure culturally respectful communications and interactions between investigators and AI/AN partners and affiliated healthcare institutions throughout the entire course of the 5-year grant. The basic goals of the Administrative Core are to support and sustain the Projects and Partnership Core, and assure that all of the research conducted in this Program conforms with the policies of NIH, the University of Washington and our partner organizations, for the benefit of our AI/AN partners and the US public. As the hub for all interactions between the different Projects and Partnership Core, and where all major Program decisions are made, the Administrative Core is essential for the coordination and execution of the Research Program.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Program Projects (P01)
Project #
1P01GM116691-01
Application #
8998297
Study Section
Special Emphasis Panel (ZGM1)
Project Start
Project End
Budget Start
2016-08-01
Budget End
2017-07-31
Support Year
1
Fiscal Year
2016
Total Cost
Indirect Cost
Name
University of Washington
Department
Pharmacology
Type
Schools of Pharmacy
DUNS #
605799469
City
Seattle
State
WA
Country
United States
Zip Code
98195
James, Rosalina D; West, Kathleen M; Claw, Katrina G et al. (2018) Responsible Research With Urban American Indians and Alaska Natives. Am J Public Health 108:1613-1616
Lee, Seung-Been; Wheeler, Marsha M; Patterson, Karynne et al. (2018) Stargazer: a software tool for calling star alleles from next-generation sequencing data using CYP2D6 as a model. Genet Med :
Au, Nicholas T; Ryman, Tove; Rettie, Allan E et al. (2018) Dietary Vitamin K and Association with Hepatic Vitamin K Status in a Yup'ik Study Population from Southwestern Alaska. Mol Nutr Food Res 62:
Cole, Allison M; Stephens, Kari A; West, Imara et al. (2018) Use of electronic health record data from diverse primary care practices to identify and characterize patients' prescribed common medications. Health Informatics J :1460458218813640
Henderson, Lindsay M; Claw, Katrina G; Woodahl, Erica L et al. (2018) P450 Pharmacogenetics in Indigenous North American Populations. J Pers Med 8:
Khan, Burhan A; Robinson, Renee; Fohner, Alison E et al. (2018) Cytochrome P450 Genetic Variation Associated with Tamoxifen Biotransformation in American Indian and Alaska Native People. Clin Transl Sci 11:312-321
Bhatt, Deepak Kumar; Basit, Abdul; Zhang, Haeyoung et al. (2018) Hepatic Abundance and Activity of Androgen- and Drug-Metabolizing Enzyme UGT2B17 Are Associated with Genotype, Age, and Sex. Drug Metab Dispos 46:888-896
Korngiebel, Diane M; Thummel, Kenneth E; Burke, Wylie (2017) Implementing Precision Medicine: The Ethical Challenges. Trends Pharmacol Sci 38:8-14
Xu, Meijuan; Bhatt, Deepak Kumar; Yeung, Catherine K et al. (2017) Genetic and Nongenetic Factors Associated with Protein Abundance of Flavin-Containing Monooxygenase 3 in Human Liver. J Pharmacol Exp Ther 363:265-274