Abstract

The Analytical and Radioimmunoassay Core will provide support for radioimmunoassays, enzyme-linked immunoassays (ELISA), HPLC, various molecular and chemical analyses, and histological studies. The core will provide assay results for a large number of hormones and cytokines as well as maintenance and supervision of key equipment in a central facility. The core will also provide tissue sections from paraffin embedded tissues, plastic embedded tissues, and frozen tissues for morphometric and stereological analyses. The morphometric and stereological measurements will be used in conjunction with immunohistochemistry to achieve the goals of the various projects. In addition, the molecular core will provide assistance with quantitation of RNA and protein, gene array, and genotyping.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Program Projects (P01)
Project #
5P01HL051971-15
Application #
7567513
Study Section
Heart, Lung, and Blood Initial Review Group (HLBP)
Project Start
Project End
Budget Start
2007-12-01
Budget End
2008-11-30
Support Year
15
Fiscal Year
2008
Total Cost
$342,408
Indirect Cost

  Institution

Name
University of Mississippi Medical Center
Department
Type
DUNS #
928824473
City
Jackson
State
MS
Country
United States
Zip Code
39216

  Publications

Edwards, Kristin S; Ashraf, Sadia; Lomax, Tyler M et al. (2018) Uncoupling protein 3 deficiency impairs myocardial fatty acid oxidation and contractile recovery following ischemia/reperfusion. Basic Res Cardiol 113:47
Lindsey, Merry L (2018) Reg-ulating macrophage infiltration to alter wound healing following myocardial infarction. Cardiovasc Res 114:1571-1572
DeLeon-Pennell, Kristine Y; Mouton, Alan J; Ero, Osasere K et al. (2018) LXR/RXR signaling and neutrophil phenotype following myocardial infarction classify sex differences in remodeling. Basic Res Cardiol 113:40
Lindsey, Merry L; Kassiri, Zamaneh; Virag, Jitka A I et al. (2018) Guidelines for measuring cardiac physiology in mice. Am J Physiol Heart Circ Physiol 314:H733-H752
Faulkner, Jessica L; Plenty, Nicole L; Wallace, Kedra et al. (2018) Selective inhibition of 20-hydroxyeicosatetraenoic acid lowers blood pressure in a rat model of preeclampsia. Prostaglandins Other Lipid Mediat 134:108-113
Spann, Redin A; Lawson, William J; Bidwell 3rd, Gene L et al. (2018) Rodent vertical sleeve gastrectomy alters maternal immune health and fetoplacental development. Clin Sci (Lond) 132:295-312
Lindsey, Merry L; Jung, Mira; Hall, Michael E et al. (2018) Proteomic analysis of the cardiac extracellular matrix: clinical research applications. Expert Rev Proteomics 15:105-112
Cates, Courtney; Rousselle, Thomas; Wang, Jinli et al. (2018) Activated protein C protects against pressure overload-induced hypertrophy through AMPK signaling. Biochem Biophys Res Commun 495:2584-2594
Mouton, Alan J; Rivera Gonzalez, Osvaldo J; Kaminski, Amanda R et al. (2018) Matrix metalloproteinase-12 as an endogenous resolution promoting factor following myocardial infarction. Pharmacol Res 137:252-258
Taylor, Erin B; Barati, Michelle T; Powell, David W et al. (2018) Plasma Cell Depletion Attenuates Hypertension in an Experimental Model of Autoimmune Disease. Hypertension 71:719-728

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