Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Program Projects (P01)
Project #
5P01HL052558-03
Application #
2029157
Study Section
Heart, Lung, and Blood Research Review Committee A (HLBA)
Project Start
1994-09-30
Project End
1999-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Washington
Department
Physiology
Type
Schools of Medicine
DUNS #
135646524
City
Seattle
State
WA
Country
United States
Zip Code
98195
Moreno-Gonzalez, Alicia; Gillis, Todd E; Rivera, Anthony J et al. (2007) Thin-filament regulation of force redevelopment kinetics in rabbit skeletal muscle fibres. J Physiol 579:313-26
Kohler, Jan; Chen, Ying; Brenner, Bernhard et al. (2003) Familial hypertrophic cardiomyopathy mutations in troponin I (K183D, G203S, K206Q) enhance filament sliding. Physiol Genomics 14:117-28
Liang, Bo; Chen, Ying; Wang, Chien-Kao et al. (2003) Ca2+ regulation of rabbit skeletal muscle thin filament sliding: role of cross-bridge number. Biophys J 85:1775-86
Regnier, Michael; Rivera, Anthony J; Wang, Chien-Kao et al. (2002) Thin filament near-neighbour regulatory unit interactions affect rabbit skeletal muscle steady-state force-Ca(2+) relations. J Physiol 540:485-97
Martyn, D A; Chase, P B; Regnier, M et al. (2002) A simple model with myofilament compliance predicts activation-dependent crossbridge kinetics in skinned skeletal fibers. Biophys J 83:3425-34
LaMadrid, M A; Chase, P B; Gordon, A M (2002) Motility assays of calcium regulation of actin filaments. Results Probl Cell Differ 36:133-48
Martyn, D A; Regnier, M; Xu, D et al. (2001) Ca2+ - and cross-bridge-dependent changes in N- and C-terminal structure of troponin C in rat cardiac muscle. Biophys J 80:360-70
Mariano, A C; Alexandre, G M; Silva, L C et al. (2001) Dimethyl sulphoxide enhances the effects of P(i) in myofibrils and inhibits the activity of rabbit skeletal muscle contractile proteins. Biochem J 358:627-36
Chase, P B; Chen, Y; Kulin, K L et al. (2000) Viscosity and solute dependence of F-actin translocation by rabbit skeletal heavy meromyosin. Am J Physiol Cell Physiol 278:C1088-98
Regnier, M; Rivera, A J; Chen, Y et al. (2000) 2-deoxy-ATP enhances contractility of rat cardiac muscle. Circ Res 86:1211-7

Showing the most recent 10 out of 25 publications