Core B. Genomics Bioinformatics A Genomics and Bioinformatics Core is proposed to enable the application of massively parallel sequencing- based approaches to advance the understanding of pathological programs of gene expression that contribute to the development of atherosclerosis and NASH. An essential aspect of all four Projects of this PPG will be to define the consequences of genetic, dietary and pharmacologic perturbations on global programs of gene expression in relevant tissues and cell types. The PPG Genomics and Bioinformatics Core will provide two complementary services to advance these efforts; 1) technical support and resources for preparation and sequencing of libraries enabling bulk RNA-Seq, single cell RNA-Seq, ATAC-Seq and ChIP-Seq assays and 2) corresponding bioinformatics and computational support to allow effective analysis of the resulting data.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Program Projects (P01)
Project #
1P01HL147835-01A1
Application #
9936773
Study Section
Heart, Lung, and Blood Initial Review Group (HLBP)
Program Officer
Kirby, Ruth
Project Start
2020-09-21
Project End
2025-07-31
Budget Start
2020-08-01
Budget End
2021-05-31
Support Year
1
Fiscal Year
2020
Total Cost
Indirect Cost
Name
University of California, San Diego
Department
Type
DUNS #
804355790
City
La Jolla
State
CA
Country
United States
Zip Code
92093