The proposed research can be divided into five different types of studies: (1) At least three studies of behavioral treatment of obesity: one will investigate the effects of spousal support with and without medication on weight loss and maintenance of weight loss. One will investigate the effects of treatment at the work site as compared with medical auspices. One will ascertain the effect of different schedules of reinforcement on weight loss in a commercial weight reduction program. (2) Three forms of non-behavioral treatment: jejunoileal surgery, gastric bypass surgery and psychoanalysis. (3) Genetic studies of obesity will consist of three twin studies: using the NRC/NAS twin register, the Kallman register of twins selected for the study of aging and Shields data on monozygotic twins brought up together and brought up apart. Adoption studies will be carried out by use of the Danish Adoption Register. (4) Intensive non-participant observation of families containing an obese and a nonobese daughter within two years of each other in age. (5) Other studies with an emphasis on both caloric intake and caloric expenditure (physical activity).

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Program Projects (P01)
Project #
5P01MH031050-09
Application #
3099009
Study Section
(TDAC)
Project Start
1979-02-01
Project End
1988-01-31
Budget Start
1985-02-01
Budget End
1986-01-31
Support Year
9
Fiscal Year
1985
Total Cost
Indirect Cost
Name
University of Pennsylvania
Department
Type
Schools of Medicine
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Berkowitz, Robert I; Stallings, Virginia A; Maislin, Greg et al. (2005) Growth of children at high risk of obesity during the first 6 y of life: implications for prevention. Am J Clin Nutr 81:140-6
Stunkard, A J; Berkowitz, R I; Schoeller, D et al. (2004) Predictors of body size in the first 2 y of life: a high-risk study of human obesity. Int J Obes Relat Metab Disord 28:503-13
Stunkard, A J; Berkowitz, R I; Stallings, V A et al. (1999) Weights of parents and infants: is there a relationship? Int J Obes Relat Metab Disord 23:159-62
Waterland, R A; Berkowitz, R I; Stunkard, A J et al. (1998) Calibrated-orifice nipples for measurement of infant nutritive sucking. J Pediatr 132:523-6
Sorensen, T I; Holst, C; Stunkard, A J (1998) Adoption study of environmental modifications of the genetic influences on obesity. Int J Obes Relat Metab Disord 22:73-81
Sorensen, T I; Stunkard, A J (1993) Does obesity run in families because of genes? An adoption study using silhouettes as a measure of obesity. Acta Psychiatr Scand Suppl 370:67-72
Sorensen, T I; Holst, C; Stunkard, A J et al. (1992) Correlations of body mass index of adult adoptees and their biological and adoptive relatives. Int J Obes Relat Metab Disord 16:227-36
Sorensen, T I; Holst, C; Stunkard, A J (1992) Childhood body mass index--genetic and familial environmental influences assessed in a longitudinal adoption study. Int J Obes Relat Metab Disord 16:705-14
Stunkard, A J; Fernstrom, M H; Price, R A et al. (1991) Weight change in depression: influence of ""disinhibition"" is mediated by body mass and other variables. Psychiatry Res 38:197-200
Stunkard, A J; Fernstrom, M H; Price, A et al. (1990) Direction of weight change in recurrent depression. Consistency across episodes. Arch Gen Psychiatry 47:857-60

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