Abstract

Processing of acoustic information varies with place along the cochlear partition and it appears that this processing is itself subject to ontogenetic change. We propose 4 interrelated projects that deal with different facets of this central theme. 1. Project 1 asks whether the place of analysis at the basal turn changes its responsiveness ontogenetically. 2. Project 2 asks whether the place code changes as a result of insult --- is it plastic? 3. Project 3 asks whether the efferent transmitter differs according to place and seeks to define its actions according to place along the partition. 4. Project 4 asks whether psychophysical performance of normal humans changes according to place along the partition.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Program Projects (P01)
Project #
5P01NS024238-02
Application #
3100111
Study Section
Communicative Disorders Review Committee (CDR)
Project Start
1986-12-01
Project End
1991-11-30
Budget Start
1987-12-01
Budget End
1988-11-30
Support Year
2
Fiscal Year
1988
Total Cost
Indirect Cost

  Institution

Name
Louisiana State University Hsc New Orleans
Department
Type
Schools of Medicine
DUNS #
782627814
City
New Orleans
State
LA
Country
United States
Zip Code
70112

  Publications

Bobbin, R P; Ceasar, G; Fallon, M (1990) Potassium induced release of GABA and other substances from the guinea pig cochlea. Hear Res 46:83-93
Hood, L J; Martin, D A; Berlin, C I (1990) Auditory evoked potentials differ at 50 milliseconds in right- and left-handed listeners. Hear Res 45:115-22
Puel, J L; Bobbin, R P; Fallon, M (1990) Salicylate, mefenamate, meclofenamate, and quinine on cochlear potentials. Otolaryngol Head Neck Surg 102:66-73
Puel, J L; Bobbin, R P; Fallon, M (1989) Suppression of auditory nerve activity in the guinea pig cochlea by 1-(p-bromobenzoyl)-piperazine-2,3-dicarboxylic acid. Brain Res 487:9-15
Littman, T; Bobbin, R P; Fallon, M et al. (1989) The quinoxalinediones DNOX, CNOX and two related congeners suppress hair cell-to-auditory nerve transmission. Hear Res 40:45-53
Harbison Jr, D C; Porter Jr, R J; Tobey, E A (1989) Shadowed and simple reaction times in stutterers and nonstutterers. J Acoust Soc Am 86:1277-84
Long, G R; Cullen Jr, J K (1988) Measures of signal processing in persons with sensorineural hearing loss below 6 kHz. J Speech Hear Res 31:659-69
Puel, J L; Bobbin, R P; Fallon, M (1988) An ipsilateral cochlear efferent loop protects the cochlea during intense sound exposure. Hear Res 37:65-9
Puel, J L; Bobbin, R P; Fallon, M (1988) The active process is affected first by intense sound exposure. Hear Res 37:53-63
Puel, J L; Bobbin, R P; Fallon, M (1988) 2-Amino-4-phosphonobutyric acid receptors are not involved in synaptic transmission from hair cells to auditory neurons. Hear Res 37:83-7

Showing the most recent 10 out of 11 publications