Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Program Projects (P01)
Project #
5P01NS033768-10
Application #
2272751
Study Section
Neurological Disorders Program Project Review B Committee (NSPB)
Project Start
1986-08-01
Project End
2000-05-31
Budget Start
1996-06-01
Budget End
1997-05-31
Support Year
10
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Wistar Institute
Department
Type
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Sanders, Iryna; Boyer, Mark; Fraser, Nigel W (2015) Early nucleosome deposition on, and replication of, HSV DNA requires cell factor PCNA. J Neurovirol 21:358-69
Oh, Jaewook; Sanders, Iryna F; Chen, Eric Z et al. (2015) Genome wide nucleosome mapping for HSV-1 shows nucleosomes are deposited at preferred positions during lytic infection. PLoS One 10:e0117471
Brinkman, Kerry K; Mishra, Prakhar; Fraser, Nigel W (2013) The half-life of the HSV-1 1.5-kb LAT intron is similar to the half-life of the 2.0-kb LAT intron. J Neurovirol 19:102-8
Hankenson, F Claire; Ruskoski, Nicholas; van Saun, Marjorie et al. (2013) Weight loss and reduced body temperature determine humane endpoints in a mouse model of ocular herpesvirus infection. J Am Assoc Lab Anim Sci 52:277-85
Volcy, Ketna; Fraser, Nigel W (2013) DNA damage promotes herpes simplex virus-1 protein expression in a neuroblastoma cell line. J Neurovirol 19:57-64
Millhouse, Scott; Wang, Xiaohe; Fraser, Nigel W et al. (2012) Direct evidence that HSV DNA damaged by ultraviolet (UV) irradiation can be repaired in a cell type-dependent manner. J Neurovirol 18:231-43
Oh, Jaewook; Ruskoski, Nicholas; Fraser, Nigel W (2012) Chromatin assembly on herpes simplex virus 1 DNA early during a lytic infection is Asf1a dependent. J Virol 86:12313-21
Jiang, Xianzhi; Chentoufi, Aziz Alami; Hsiang, Chinhui et al. (2011) The herpes simplex virus type 1 latency-associated transcript can protect neuron-derived C1300 and Neuro2A cells from granzyme B-induced apoptosis and CD8 T-cell killing. J Virol 85:2325-32
Millhouse, Scott; Su, Ying-Hsiu; Zhang, Xianchao et al. (2010) Evidence that herpes simplex virus DNA derived from quiescently infected cells in vitro, and latently infected cells in vivo, is physically damaged. J Neurovirol 16:384-98
Smith, Sheryl T; Wickramasinghe, Priyankara; Olson, Andrew et al. (2009) Genome wide ChIP-chip analyses reveal important roles for CTCF in Drosophila genome organization. Dev Biol 328:518-28

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