This project represents a continuing effort to promote and sustain development of the biomedical research community in Montana. Long range objectives are to strengthen the quality and competitiveness of biomedical investigators in Montana, and strengthen facilities, programs and resources that are essential for their development. The scope of this project is statewide, encompassing all units of the Montana University System and private research institutes engaged in biomedical research. To accomplish objectives of this phase of the project we will support four scientific projects that best fulfill criteria for faculty development and the strengthening of research capabilities in Montana; and further strengthen the research infrastructure through development of a transgenic mouse facility at the McLaughlin Research Institute and a CNS cell culture facility at the University of Montana, continue to enhance research in molecular biology and strengthen developing neuroscience groups at Montana State University and the University of Montana. In addition, we will continue a scientific advising and review process to provide critical input that will improve the competitiveness of individual PIs, and that will help identify projects that can be developed in subsequent phases of this project.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Exploratory Grants (P20)
Project #
1P20RR010169-01
Application #
2285629
Study Section
Special Emphasis Panel (SRC)
Project Start
1995-03-01
Project End
1997-02-28
Budget Start
1995-03-01
Budget End
1996-02-29
Support Year
1
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of Montana
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
City
Missoula
State
MT
Country
United States
Zip Code
59812
Hall, Brian; Burnett, Andrea; Christians, Alicia et al. (2010) Thermodynamics of peptide and non-peptide interactions with the human 5HT1a receptor. Pharmacology 86:6-14
Thiagaraj, Harish V; Ortiz, Thomas C; Devereaux Jr, Marvin C et al. (2007) Regulation of G proteins by human 5-HT1a receptor TM3/i2 and TM5/i3 loop peptides. Neurochem Int 50:109-18
Babcock, A Michael; Wright, J; Bjerkness, D et al. (2002) Effects of prior apparatus experience and novelty of testing environment on locomotor activity following MK-801. Physiol Behav 77:177-81
Minnick, M F; Anderson, B E (2000) Bartonella interactions with host cells. Subcell Biochem 33:97-123
Ortiz, T C; Devereaux Jr, M C; Parker, K K (2000) Structural variants of a human 5-HT1a receptor intracellular loop 3 peptide. Pharmacology 60:195-202
Fulgham, D L; Widhalm, S R; Martin, S et al. (1999) FGF-2 dependent angiogenesis is a latent phenotype in basic fibroblast growth factor transgenic mice. Endothelium 6:185-95
Babcock, A M; Liu, H; Paden, C M et al. (1999) In vivo glutamate neurotoxicity is associated with reductions in calcium/calmodulin-dependent protein kinase II immunoreactivity. J Neurosci Res 56:36-43
Battisti, J M; Smitherman, L S; Samuels, D S et al. (1998) Mutations in Bartonella bacilliformis gyrB confer resistance to coumermycin A1. Antimicrob Agents Chemother 42:2906-13
Hayataka, K; O'Connor, M F; Kinzler, N et al. (1998) A bioactive peptide from the transmembrane 5-intracellular loop 3 region of the human 5HT1a receptor. Biochem Cell Biol 76:657-60
Mitchell, S J; Minnick, M F (1997) A carboxy-terminal processing protease gene is located immediately upstream of the invasion-associated locus from Bartonella bacilliformis. Microbiology 143 ( Pt 4):1221-33

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