The goal of the Pilot/Exploratory Core (PEC) is to facilitate innovative and methodologically rigorous research that enhances our understanding of the etiology and mechanisms of the sarcopenia of aging. P/EC activities will incorporate new technologies into aging research, stimulate translational research, and facilitate novel interdisciplinary strategies that ultimately lead to interventions ameliorating the loss of muscle function that occurs with aging.
Specific aims of this P/EC are: 1) solicit and select the most meritorious research proposals for P/EC funding;2) provide investigators of P/EC studies with access to resources from other OAIC cores and institutional research facilities;3) identify potential opportunities for co-sponsorship of P/EC studies;4) monitor the progress of P/EC studies;5 ) provide assistance and mentorship so that P/EC studies can be successfully developed into independently funded grant applications;and 6) ensure the safety and protection of human subjects enrolled in P/EC studies. The P/EC will contribute to the goals of the UTMB OAIC by encouraging and supporting a research team of junior and senior investigators to conduct innovative and forward-looking research that supports our OAIC objectives. Further, the P/EC will bring to bear the combined resources of the OAIC, the Sealy Center on Aging, the Center for Population Health and Health Disparities, the General Clinical Research Center (GCRC), and UTMB research cores, to facilitate studies investigating the biology and physiology related to decreases in muscle function with aging.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Center Core Grants (P30)
Project #
5P30AG024832-05
Application #
7812032
Study Section
Special Emphasis Panel (ZAG1)
Project Start
Project End
Budget Start
2009-05-01
Budget End
2010-04-30
Support Year
5
Fiscal Year
2009
Total Cost
$364,550
Indirect Cost
Name
University of Texas Medical Br Galveston
Department
Type
DUNS #
800771149
City
Galveston
State
TX
Country
United States
Zip Code
77555
Downer, Brian; Al Snih, Soham; Howrey, Bret T et al. (2018) Combined effects of cognitive impairment and pre-frailty on future frailty and death in older Mexican Americans. Aging Ment Health :1-8
Goodwin, James S; Salameh, Habeeb; Zhou, Jie et al. (2018) Association of Hospitalist Years of Experience With Mortality in the Hospitalized Medicare Population. JAMA Intern Med 178:196-203
Salinas, Jennifer J; Gonzalez, Jennifer M Reingle; Al Snih, Soham (2018) Type 2 diabetes, depressive symptoms and disability over a 15-year follow-up period in older Mexican Americans living in the southwestern United States. J Diabetes Complications 32:75-82
Hong, Ickpyo; Karmarkar, Amol; Chan, Winston et al. (2018) Discharge Patterns for Ischemic and Hemorrhagic Stroke Patients Going From Acute Care Hospitals to Inpatient and Skilled Nursing Rehabilitation. Am J Phys Med Rehabil 97:636-645
Jamadar, Sharna D; Sforazzini, Francesco; Raniga, Parnesh et al. (2018) Sexual Dimorphism of Resting-State Network Connectivity in Healthy Ageing. J Gerontol B Psychol Sci Soc Sci :
McNeil, John J; Woods, Robyn L; Nelson, Mark R et al. (2018) Effect of Aspirin on Disability-free Survival in the Healthy Elderly. N Engl J Med 379:1499-1508
Asghar, Rabia; Chondronikola, Maria; Dillon, Edgar L et al. (2018) Quantification of muscle triglyceride synthesis rate requires an adjustment for total triglyceride content. J Lipid Res 59:2018-2024
Goodwin, James S; Li, Shuang; Middleton, Addie et al. (2018) Differences Between Skilled Nursing Facilities in Risk of Subsequent Long-Term Care Placement. J Am Geriatr Soc 66:1880-1886
Collins, Diane M; Downer, Brian; Kumar, Amit et al. (2018) Impact of Multiple Chronic Conditions on Activity Limitations Among Older Mexican-American Care Recipients. Prev Chronic Dis 15:E51
Moro, Tatiana; Brightwell, Camille R; Deer, Rachel R et al. (2018) Muscle Protein Anabolic Resistance to Essential Amino Acids Does Not Occur in Healthy Older Adults Before or After Resistance Exercise Training. J Nutr 148:900-909

Showing the most recent 10 out of 408 publications