Abstract

The Harvard University (HU) CFAR Biostatistics Core is a distributed Core, with offices at three sites: the Dana Farber Cancer Institute (DFCI), the Massachusetts General Hospital (MGH), and the Harvard School of Public Health (HSPH);these three locations provide services to all the HU CFAR institutions. The Biostatistics Core provides statistical collaboration and consultation for HIV-related laboratory, animal, clinical, and outcome studies to CFAR members and their trainees and to investigators who are new to HIV research. Broadly, the services of the biostatistics core include: design (including sample size calculations and analysis plans for all studies and database management for clinical studies), analysis of data (including model results and graphs), and training (in statistical methods, computer packages, and graphical illustration).

Public Health Relevance

The Biostatistics Core improves the efficiency of studies and prevents fatal design flaws. Another function of the Biostatistics Core is to analyze data for investigators who are not trained to do more complicated analyses or to check whether the assumptions of an analysis method are violated.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Center Core Grants (P30)
Project #
2P30AI060354-06
Application #
7685012
Study Section
Special Emphasis Panel (ZAI1-SV-A (J3))
Project Start
2009-08-11
Project End
2014-07-31
Budget Start
2009-07-01
Budget End
2010-07-31
Support Year
6
Fiscal Year
2009
Total Cost
$693,717
Indirect Cost

  Institution

Name
Harvard University
Department
Type
DUNS #
082359691
City
Cambridge
State
MA
Country
United States
Zip Code
02138

  Publications

Ordovas-Montanes, Jose; Dwyer, Daniel F; Nyquist, Sarah K et al. (2018) Allergic inflammatory memory in human respiratory epithelial progenitor cells. Nature 560:649-654
Joglekar, Alok V; Liu, Zhe; Weber, Jeffrey K et al. (2018) T cell receptors for the HIV KK10 epitope from patients with differential immunologic control are functionally indistinguishable. Proc Natl Acad Sci U S A 115:1877-1882
Bassett, Ingrid Valerie; Huang, Mingshu; Cloete, Christie et al. (2018) Assessing the completeness and accuracy of South African National Laboratory CD4 and viral load data: a cross-sectional study. BMJ Open 8:e021506
Calabrese, Sarah K; Earnshaw, Valerie A; Magnus, Manya et al. (2018) Sexual Stereotypes Ascribed to Black Men Who Have Sex with Men: An Intersectional Analysis. Arch Sex Behav 47:143-156
Rogers, Brooke G; Mendez, Noelle A; Mimiaga, Matthew J et al. (2018) ""I Wasn't in My Right Mind"": Qualitative Findings on the Impact of Alcohol on Condom Use in Patients Living with HIV/AIDS in Brazil, Thailand, and Zambia (HPTN 063). Int J Behav Med :
Alvi, Raza M; Neilan, Anne M; Tariq, Noor et al. (2018) Protease Inhibitors and Cardiovascular Outcomes in Patients With HIV and Heart Failure. J Am Coll Cardiol 72:518-530
Bassett, Ingrid V; Xu, Ai; Govere, Sabina et al. (2018) Contraception and PrEP in South African Hair Salons: Owner, Stylist, and Client Views. J Acquir Immune Defic Syndr 79:e78-e81
Looby, Sara E; Psaros, Christina; Raggio, Greer et al. (2018) Association between HIV status and psychological symptoms in perimenopausal women. Menopause 25:648-656
Shapiro, Adrienne E; Hong, Ting; Govere, Sabina et al. (2018) C-reactive protein as a screening test for HIV-associated pulmonary tuberculosis prior to antiretroviral therapy in South Africa. AIDS 32:1811-1820
Clayton, Kiera L; Collins, David R; Lengieza, Josh et al. (2018) Resistance of HIV-infected macrophages to CD8+ T lymphocyte-mediated killing drives activation of the immune system. Nat Immunol 19:475-486

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